Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 5/20 | 0.58 |
| ▸ | ADAMTS4 | O75173 | 4/20 | 0.55 |
| ▸ | MMP2 | P08253 | 8/20 | 0.50 |
| ▸ | MMP13 | P45452 | 7/20 | 0.50 |
| ▸ | MMP3 | P08254 | 6/20 | 0.50 |
| ▸ | MMP1 | P03956 | 5/20 | 0.50 |
| ▸ | MMP7 | P09237 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2846313 | 0.79 | ADRB3 (0.47) | ADAMTS4MMP2MMP13MMP1MEN1 | |
| SCHEMBL8873505 | 0.75 | MEN1 (0.56) | MEN1KMT2AALDH1A1 | |
| SCHEMBL8873509 | 0.75 | MEN1 (0.56) | MEN1KMT2AALDH1A1 | |
| SCHEMBL14602231 | 0.74 | MMP9 (0.82) | MMP9ADAMTS4MMP2MMP13MMP3 | |
| SCHEMBL19627057 | 0.72 | PTGS1 (0.49) | MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL10346803 | 0.72 | NPC1 (0.53) | ALDH1A1HPGD | |
| SCHEMBL19614361 | 0.72 | RAB9A (0.55) | MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL19614362 | 0.72 | RAB9A (0.55) | MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL2842038 | 0.72 | CASP3 (0.57) | ADAMTS4MMP2MMP13MMP1MEN1 | |
| SCHEMBL2838360 | 0.71 | TP53 (0.47) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160903-B2 | Sulfonylaminocarboxylic acids | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2007-01-09 | — | — | US | disclosed |
| US-7160903-B2 | Sulfonylaminocarboxylic acids | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2007-01-09 | — | — | US | disclosed |