Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27947357 | 0.87 | TRPV4 (0.40) | TRPV4ALDH1A1KDM4EMAPTMEN1 | |
| SCHEMBL27947352 | 0.84 | TRPV4 (0.39) | TRPV4ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL27930552 | 0.84 | TRPV4 (0.39) | TRPV4ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL6982992 | 0.75 | AR (0.37) | TRPV4ALDH1A1KDM4ERECQLTDP1 | |
| SCHEMBL23846800 | 0.74 | TDP1 (0.50) | TRPV4ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL16556066 | 0.74 | TRPV4 (0.43) | TRPV4 | |
| SCHEMBL1392608 | 0.74 | ALDH1A1 (0.45) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL16555432 | 0.74 | TRPV4 (0.43) | TRPV4ALDH1A1KDM4EMAPTMEN1 | |
| SCHEMBL2375554 | 0.73 | TRPV4 (0.39) | TRPV4TSHRMAOAMAOB | |
| SCHEMBL3074213 | 0.73 | MAOA (0.45) | TRPV4ALDH1A1KDM4EMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070010645-A1 | Red-shifted water dispersible IR dyes | SILVERBROOK RESEARCH PTY LTD | 2007-01-11 | — | — | US | disclosed |