Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4101467 | 0.85 | ALDH1A1 (0.51) | SMN1; SMN2HTTPOLBALDH1A1LMNA | |
| SCHEMBL28124286 | 0.82 | KDM4E (0.55) | SMN1; SMN2HTTPOLBALDH1A1NPC1 | |
| SCHEMBL8950197 | 0.78 | KDM4E (0.47) | SMN1; SMN2HTTPOLBALDH1A1LMNA | |
| SCHEMBL27448977 | 0.77 | MAPT (0.55) | SMN1; SMN2HTTPOLBALDH1A1LMNA | |
| SCHEMBL27486663 | 0.77 | KMT2A (0.45) | SMN1; SMN2HTTPOLBALDH1A1NPC1 | |
| SCHEMBL215343 | 0.77 | TDP1 (0.46) | SMN1; SMN2HTTPOLBALDH1A1LMNA | |
| SCHEMBL265603 | 0.76 | L3MBTL1 (0.56) | HTTPOLBALDH1A1LMNANPC1 | |
| SCHEMBL18138425 | 0.76 | TDP1 (0.45) | SMN1; SMN2HTTPOLBALDH1A1LMNA | |
| SCHEMBL7815989 | 0.75 | NR1H4 (0.46) | SMN1; SMN2HTTPOLBALDH1A1LMNA | |
| SCHEMBL11748681 | 0.75 | KDM4E (0.44) | SMN1; SMN2HTTPOLBALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120288885-A1 | METHOD AND KIT FOR MEASURING ENZYMATIC ACTIVITIES OF VARIOUS CYTOCHROME P450 MOLECULE SPECIES COMPREHENSIVELY AND WITH HIGH EFFICIENCY | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLGOY (JP) | 2012-11-15 | — | — | US | disclosed |
| WO-2011027718-A1 | METHOD AND KIT FOR MEASURING ENZYMATIC ACTIVITIES OF VARIOUS CYTOCHROME P450 MOLECULE SPECIES COMPREHENSIVELY AND WITH HIGH EFFICIENCY | 国立大学法人神戸大学 (JP) | 2011-03-10 | — | — | WO | disclosed |