Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.60 |
| ▸ | POLB | P06746 | 5/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | LDHA | P00338 | 1/20 | 0.48 |
| ▸ | LDHB | P07195 | 1/20 | 0.48 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21426983 | 0.81 | MAPT (0.69) | ALDH1A1KDM4EMAPTCYP3A4HPGD | |
| SCHEMBL8243143 | 0.81 | ALDH1A1 (0.67) | ALDH1A1KDM4EPOLBTDP1L3MBTL1 | |
| SCHEMBL25977802 | 0.81 | ALDH1A1 (0.62) | ALDH1A1KDM4EPOLBTDP1L3MBTL1 | |
| SCHEMBL26168426 | 0.80 | ALDH1A1 (0.53) | ALDH1A1KDM4EPOLBTDP1L3MBTL1 | |
| SCHEMBL14324716 | 0.79 | ALDH1A1 (0.60) | ALDH1A1KDM4EPOLBTDP1L3MBTL1 | |
| SCHEMBL624327 | 0.79 | ALDH1A1 (0.60) | ALDH1A1KDM4EPOLBTDP1L3MBTL1 | |
| SCHEMBL7328684 | 0.79 | ALDH1A1 (0.64) | ALDH1A1KDM4EPOLBTDP1L3MBTL1 | |
| SCHEMBL14324626 | 0.79 | ALDH1A1 (0.60) | ALDH1A1KDM4EPOLBTDP1L3MBTL1 | |
| SCHEMBL2324212 | 0.79 | ALDH1A1 (0.60) | ALDH1A1KDM4EPOLBTDP1L3MBTL1 | |
| SCHEMBL6415208 | 0.78 | ALDH1A1 (0.76) | ALDH1A1KDM4EPOLBTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1523485-B1 | 3-FURANYL ANALOGS OF TOXOFLAVINE AS KINASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2007-02-14 | — | — | EP | disclosed |