Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.55 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.55 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.55 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8243143 | 0.81 | ALDH1A1 (0.67) | ALDH1A1KDM4ELMNAPOLBTDP1 | |
| SCHEMBL25977802 | 0.81 | ALDH1A1 (0.62) | ALDH1A1KDM4ELMNAPOLBTDP1 | |
| SCHEMBL14324716 | 0.79 | ALDH1A1 (0.60) | ALDH1A1KDM4ELMNAPOLBTDP1 | |
| SCHEMBL624327 | 0.79 | ALDH1A1 (0.60) | ALDH1A1KDM4ELMNAPOLBTDP1 | |
| SCHEMBL2324212 | 0.79 | ALDH1A1 (0.60) | ALDH1A1KDM4ELMNAPOLBTDP1 | |
| SCHEMBL14324626 | 0.79 | ALDH1A1 (0.60) | ALDH1A1KDM4ELMNAPOLBTDP1 | |
| SCHEMBL14608669 | 0.79 | ALDH1A1 (0.60) | ALDH1A1KDM4ELMNAPOLBTDP1 | |
| SCHEMBL1199113 | 0.79 | KDM4E (0.67) | ALDH1A1KDM4ELMNAPOLBTDP1 | |
| SCHEMBL7320108 | 0.79 | HPGD (0.66) | ALDH1A1KDM4ELMNAPOLBL3MBTL1 | |
| SCHEMBL31416495 | 0.79 | ALDH1A1 (0.60) | ALDH1A1KDM4ELMNAPOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119330967-B | MET transcription inhibitor and preparation method and application thereof | 中国药科大学 | 2025-04-25 | — | — | CN | disclosed |
| CN-119330967-A | MET transcription inhibitor and preparation method and application thereof | 中国药科大学 | 2025-01-21 | — | — | CN | disclosed |
| US-4882354-A | N-hydroxy-5-phenyl-2-furancarboximidamides useful as cardiotonic agents | NORWICH EATON PHARMACEUTICALS, INC. (US) | 1989-11-21 | — | — | US | disclosed |
| EP-0321431-A1 | N-hydroxy-5-phenyl-2-furancarboximidamides useful as cardiotonic agents | Norwich Eaton Pharmaceuticals, Inc. (US) | 1989-06-21 | — | — | EP | disclosed |