Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.62 |
| ▸ | POLB | P06746 | 5/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | LDHA | P00338 | 1/20 | 0.49 |
| ▸ | LDHB | P07195 | 1/20 | 0.49 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.49 |
| ▸ | PRKDC | P78527 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8243143 | 0.82 | ALDH1A1 (0.67) | ALDH1A1KDM4EPOLBTDP1L3MBTL1 | |
| SCHEMBL7328684 | 0.81 | ALDH1A1 (0.64) | ALDH1A1KDM4EPOLBTDP1L3MBTL1 | |
| SCHEMBL624327 | 0.81 | ALDH1A1 (0.60) | ALDH1A1KDM4EPOLBTDP1L3MBTL1 | |
| SCHEMBL14324626 | 0.81 | ALDH1A1 (0.60) | ALDH1A1KDM4EPOLBTDP1L3MBTL1 | |
| SCHEMBL14608669 | 0.81 | ALDH1A1 (0.60) | ALDH1A1KDM4EPOLBTDP1L3MBTL1 | |
| SCHEMBL14324716 | 0.81 | ALDH1A1 (0.60) | ALDH1A1KDM4EPOLBTDP1L3MBTL1 | |
| SCHEMBL2324212 | 0.81 | ALDH1A1 (0.60) | ALDH1A1KDM4EPOLBTDP1L3MBTL1 | |
| SCHEMBL622653 | 0.79 | KDM4E (0.66) | ALDH1A1KDM4EPOLBTDP1L3MBTL1 | |
| SCHEMBL28307056 | 0.79 | ALDH1A1 (0.66) | ALDH1A1KDM4EPOLBTDP1L3MBTL1 | |
| SCHEMBL12177745 | 0.77 | ALDH1A1 (0.69) | ALDH1A1KDM4EPOLBTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146244-A1 | BENZODIOXANE DERIVATIVE COMPOUNDS AND MEDICAL USE THEREOF | 재단법인 한국파스퇴르연구소 | 2023-08-03 | — | — | WO | disclosed |