Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 6/20 | 0.57 |
| ▸ | PPARG | P37231 | 5/20 | 0.57 |
| ▸ | PPARD | Q03181 | 2/20 | 0.57 |
| ▸ | ITGAV | P06756 | 5/20 | 0.52 |
| ▸ | ACE | P12821 | 1/20 | 0.52 |
| ▸ | CTSS | P25774 | 5/20 | 0.51 |
| ▸ | CTSK | P43235 | 5/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.51 |
| ▸ | CTSB | P07858 | 1/20 | 0.51 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3866896 | 0.90 | PPARA (0.49) | PPARAPPARGPPARDITGAVCTSS | |
| SCHEMBL606574 | 0.90 | PPARA (0.60) | PPARAPPARGPPARDITGAVACE | |
| SCHEMBL607141 | 0.90 | PPARA (0.60) | PPARAPPARGPPARDITGAVACE | |
| SCHEMBL6379577 | 0.88 | CTSS (0.51) | PPARAPPARGPPARDCTSSCTSK | |
| SCHEMBL15328079 | 0.88 | PPARA (0.51) | PPARAPPARGPPARDACECTSS | |
| SCHEMBL346337 | 0.84 | ALDH1A1 (0.57) | PPARAPPARGPPARDCTSK | |
| SCHEMBL6379646 | 0.84 | CTSS (0.53) | PPARAPPARGPPARDACECTSS | |
| SCHEMBL8239220 | 0.84 | ALDH1A1 (0.57) | PPARAPPARGPPARDCTSK | |
| SCHEMBL9848834 | 0.83 | CTSK (0.52) | PPARAPPARGPPARDCTSSCTSK | |
| SCHEMBL8294590 | 0.82 | PPARA (0.51) | PPARAPPARGPPARDACECTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050085516-A1 | 2-W-diaminocarboxylic acid compounds | BASF AKTIENGESELLSCHAFT (DE) | 2005-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050085516-A1 | 2-W-diaminocarboxylic acid compounds | DDT, ANTXR2, MTX2 | PPARA 160/4885PPARG 65/4885PPARD 177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.