Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 7/20 | 0.44 |
| ▸ | CTSS | P25774 | 5/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CCKAR | P32238 | 1/20 | 0.36 |
| ▸ | CCKBR | P32239 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9565659 | 0.84 | CTSS (0.47) | CTSKCTSSIDO1ALDH1A1KDM4E | |
| SCHEMBL7301432 | 0.84 | CTSS (0.47) | CTSKCTSSIDO1ALDH1A1KDM4E | |
| SCHEMBL28499087 | 0.83 | EPHX2 (0.39) | IDO1GAAKDM4EGLAMAPT | |
| SCHEMBL28799343 | 0.83 | TDP1 (0.44) | GAAMAPTKMT2AMEN1HDAC4 | |
| SCHEMBL6741998 | 0.81 | CTSK (0.42) | CTSKCTSSIDO1GAAALDH1A1 | |
| SCHEMBL4174487 | 0.79 | CTSK (0.46) | CTSKCTSSIDO1GAAALDH1A1 | |
| SCHEMBL12767866 | 0.75 | CTSK (0.52) | CTSKCTSSTSHRCYP1A2CYP2C9 | |
| SCHEMBL9315139 | 0.74 | IDO1 (0.45) | CTSKCTSSIDO1GAACYP1A2 | |
| SCHEMBL8527595 | 0.73 | CTSS (0.51) | CTSKCTSSIDO1KMT2ACTSL | |
| SCHEMBL1001000 | 0.73 | GAA (0.40) | GAAALDH1A1TSHRKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501795-B1 | CINNAMIC ACID AMIDES | BAYER HEALTHCARE AG (DE) | 2007-02-28 | — | — | EP | disclosed |