Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.38 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14609954 | 0.94 | LMNA (0.48) | LMNAMAPTL3MBTL1PLA2G1BATG4B | |
| SCHEMBL14610592 | 0.90 | PARP1 (0.39) | TRPM8LPAR1 | |
| SCHEMBL14610247 | 0.89 | TRPM8 (0.45) | LMNAMAPTL3MBTL1KMT2ATRPM8 | |
| SCHEMBL14610246 | 0.88 | TRPM8 (0.41) | KMT2ATRPM8ALDH1A1KDM4ELPAR1 | |
| SCHEMBL14610069 | 0.84 | TDP1 (0.46) | KMT2ARAB9APOLBLPAR1GAA | |
| SCHEMBL14610068 | 0.84 | TDP1 (0.46) | LMNAGAA | |
| SCHEMBL14078307 | 0.83 | MRGPRX4 (0.46) | RAB9ATRPM8ALDH1A1LPAR1GAA | |
| SCHEMBL5303445 | 0.82 | TRPM8 (0.48) | LMNAMAPTL3MBTL1KMT2ATRPM8 | |
| SCHEMBL5302863 | 0.81 | LMNA (0.55) | LMNAMAPTL3MBTL1PLA2G1BATG4B | |
| SCHEMBL14610199 | 0.81 | TRPM8 (0.52) | LMNAMAPTL3MBTL1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007017093-A1 | SUBSTITUTED 2-BENZYLOXY-BENZOIC ACID AMIDE DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2007-02-15 | — | — | WO | disclosed |