Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.39 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.38 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14610068 | 0.90 | TDP1 (0.46) | TDP1TSHRGAASIGMAR1TMEM97 | |
| SCHEMBL14609954 | 0.86 | LMNA (0.48) | POLBACKR3SIGMAR1TMEM97RAB9A | |
| SCHEMBL5332700 | 0.84 | TSHR (0.56) | TDP1TSHRACKR3SIGMAR1TMEM97 | |
| SCHEMBL14609986 | 0.84 | LMNA (0.42) | POLBGAARAB9AKMT2ALPAR1 | |
| SCHEMBL14609953 | 0.81 | TSHR (0.60) | TDP1TSHRPOLBGAAKMT2A | |
| SCHEMBL31687499 | 0.78 | SIGMAR1 (0.58) | TDP1POLBGAAACKR3SIGMAR1 | |
| SCHEMBL14610592 | 0.78 | PARP1 (0.39) | LPAR1 | |
| SCHEMBL31687548 | 0.76 | ACKR3 (0.53) | TDP1POLBGAAACKR3SIGMAR1 | |
| SCHEMBL3702941 | 0.76 | NAMPT (0.61) | TDP1POLBGAANAMPTCA1 | |
| SCHEMBL3437047 | 0.75 | GAA (0.56) | TDP1POLBGAASIGMAR1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007017093-A1 | SUBSTITUTED 2-BENZYLOXY-BENZOIC ACID AMIDE DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2007-02-15 | — | — | WO | disclosed |