Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenyl(Methyl)Semicarbazone SCHEMBL17119918 | 0.75 | ALDH1A1 (1.00) | LMNAALDH1A1CYP1A2CYP2C9CYP2C19 | |
| Phenyl(Methyl)Semicarbazone SCHEMBL28048924 | 0.75 | ALDH1A1 (1.00) | LMNAALDH1A1CYP1A2CYP2C9CYP2C19 | |
| Phenyl(Methyl)Semicarbazone SCHEMBL27835565 | 0.75 | ALDH1A1 (1.00) | LMNAALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL14906955 | 0.74 | LMNA (0.72) | LMNAALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL22607788 | 0.74 | LMNA (0.77) | LMNAALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL20080851 | 0.74 | LMNA (0.72) | LMNAALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7162464 | 0.73 | NPSR1 (0.42) | LMNAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL16194649 | 0.72 | LMNA (0.70) | LMNAALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL17560861 | 0.72 | LMNA (1.00) | LMNAALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL16194650 | 0.72 | LMNA (0.70) | LMNAALDH1A1CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007014023-A1 | THIAZOLIDINONES, OXAZOLIDINONES, AND PYRROLIDINONES FOR HBV | VALEANT RESEARCH & DEVELOPMENT (US) | 2007-02-01 | — | — | WO | disclosed |