Phenyl(Methyl)Semicarbazone

Phenyl(Methyl)Semicarbazone

SCHEMBL28048924

CC(=NNC(N)=O)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 1.00
LMNA P02545 3/20 1.00
MAPT P10636 3/20 0.72
POLB P06746 1/20 0.72
CYP1A2 P05177 2/20 0.69
CYP2C19 P33261 2/20 0.69
CYP2C9 P11712 1/20 0.69
ATM Q13315 1/20 0.68
METTL3 Q86U44 1/20 0.68
SMN1; SMN2 Q16637 4/20 0.66
MEN1 O00255 4/20 0.66
KMT2A Q03164 4/20 0.66
NPC1 O15118 3/20 0.58
RAB9A P51151 3/20 0.58
NFKB1 P19838 2/20 0.58
NFKB2 Q00653 2/20 0.58
RELA Q04206 2/20 0.58
CYP3A4 P08684 1/20 0.58
CASP3 P42574 1/20 0.58
SENP7 Q9BQF6 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenyl(Methyl)Semicarbazone SCHEMBL27835565 1.00 ALDH1A1 (1.00) ALDH1A1LMNAMAPTPOLBCYP1A2
Phenyl(Methyl)Semicarbazone SCHEMBL17119918 1.00 ALDH1A1 (1.00) ALDH1A1LMNAMAPTPOLBCYP1A2
SCHEMBL22607788 0.87 LMNA (0.77) ALDH1A1LMNAMAPTPOLBCYP1A2
SCHEMBL7752872 0.84 MAPT (0.78) ALDH1A1LMNAMAPTPOLBCYP1A2
SCHEMBL27177997 0.84 MAPT (0.78) ALDH1A1LMNAMAPTPOLBCYP1A2
SCHEMBL12186262 0.84 MAPT (0.78) ALDH1A1LMNAMAPTPOLBCYP1A2
SCHEMBL14938560 0.84 MAPT (0.78) ALDH1A1LMNAMAPTPOLBCYP1A2
Phenyl(Methyl)Thiosemicarbazone SCHEMBL27879446 0.84 METTL3 (0.90) ALDH1A1LMNAMAPTPOLBATM
SCHEMBL20080851 0.83 LMNA (0.72) ALDH1A1LMNAMAPTPOLBCYP1A2
SCHEMBL14906955 0.83 LMNA (0.72) ALDH1A1LMNAMAPTPOLBCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114628706-B Catalyst for proton exchange membrane fuel cell and preparation method thereof 西安凯立新材料股份有限公司 2024-02-13 CN claimed
CN-113634283-B Copper-based composite catalyst and method for hydrochlorination of acetylene 西安凯立新材料股份有限公司 2023-06-30 CN claimed
CN-114628706-A Catalyst for proton exchange membrane fuel cell and preparation method thereof 西安凯立新材料股份有限公司 2022-06-14 CN claimed
CN-114628706-B Catalyst for proton exchange membrane fuel cell and preparation method thereof 西安凯立新材料股份有限公司 2024-02-13 CN disclosed
CN-113634283-B Copper-based composite catalyst and method for hydrochlorination of acetylene 西安凯立新材料股份有限公司 2023-06-30 CN disclosed
CN-114628706-A Catalyst for proton exchange membrane fuel cell and preparation method thereof 西安凯立新材料股份有限公司 2022-06-14 CN disclosed
CN-105130843-A Benzyl hydrazone compound and preparation method and uses thereof UNIV CHINA AGRICULTURAL 2015-12-09 CN disclosed