Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4114149 | 0.75 | PTGER4 (0.38) | — | |
| SCHEMBL2207699 | 0.73 | ALDH1A1 (0.44) | — | |
| SCHEMBL4105346 | 0.73 | KMT2A (0.34) | ADORA2B | |
| SCHEMBL13871659 | 0.65 | KMT2A (0.34) | ADORA2B | |
| SCHEMBL14610314 | 0.65 | KMT2A (0.33) | — | |
| SCHEMBL13871657 | 0.64 | ALDH1A1 (0.34) | — | |
| SCHEMBL13871658 | 0.63 | FLT3 (0.32) | — | |
| SCHEMBL4106475 | 0.63 | PTGER4 (0.34) | — | |
| SCHEMBL13639149 | 0.62 | PTGER3 (0.39) | — | |
| SCHEMBL4116123 | 0.61 | PTGER4 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007014454-A1 | EP4 RECEPTOR AGONIST, COMPOSITIONS AND METHODS THEREOF | MERCK FROSST CANADA LTD. (CA) | 2007-02-08 | — | — | WO | disclosed |