Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5149285 | 0.88 | HDAC4 (0.60) | HDAC4HDAC2HDAC8HPGDALDH1A1 | |
| SCHEMBL14003500 | 0.84 | MAPT (0.57) | HPGDALDH1A1MAPK1MAPTKMT2A | |
| SCHEMBL1957953 | 0.83 | SMN1; SMN2 (0.56) | HPGDALDH1A1HSD17B10MAPK1MAPT | |
| SCHEMBL23747381 | 0.81 | MAPT (0.54) | HDAC4HDAC2HDAC8HPGDALDH1A1 | |
| SCHEMBL16109474 | 0.79 | HDAC4 (0.65) | HDAC4HDAC2HDAC8HPGDALDH1A1 | |
| SCHEMBL14397805 | 0.78 | SMN1; SMN2 (0.58) | HPGDALDH1A1CYP3A4MAPK1KMT2A | |
| SCHEMBL29581343 | 0.78 | MAPT (0.68) | HPGDALDH1A1CYP3A4HSD17B10MAPK1 | |
| SCHEMBL885028 | 0.78 | MAPT (0.68) | HPGDALDH1A1CYP3A4HSD17B10MAPK1 | |
| SCHEMBL5150983 | 0.78 | SMN1; SMN2 (0.66) | HDAC4HDAC2HDAC8HPGDALDH1A1 | |
| SCHEMBL22319299 | 0.78 | ALDH1A1 (0.57) | HDAC8HPGDALDH1A1CYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007017289-A2 | ACYLTRYPTOPHANOLS FOR FERTILITY CONTROL | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-02-15 | — | — | WO | disclosed |