Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.52 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ERN1 | O75460 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14610550 | 0.88 | HDAC4 (0.60) | HDAC4HDAC2HDAC8CYP2D6CYP2C9 | |
| SCHEMBL5150983 | 0.87 | SMN1; SMN2 (0.66) | HDAC4HDAC2HDAC8CYP2D6CYP2C9 | |
| SCHEMBL536179 | 0.83 | HTT (0.62) | ALDH1A1HPGDKDM4EKMT2AAKR1C3 | |
| SCHEMBL17454033 | 0.83 | SMN1; SMN2 (0.55) | KDM4EPOLBMEN1KMT2ARAB9A | |
| SCHEMBL29263230 | 0.83 | HPGD (0.58) | CYP2D6ALDH1A1HPGDMAPTKDM4E | |
| SCHEMBL8204969 | 0.82 | RAB9A (0.54) | CYP2D6CYP2C9ALDH1A1HPGDKDM4E | |
| SCHEMBL9634001 | 0.82 | HTT (0.61) | ALDH1A1HPGDKDM4EKMT2AAKR1C3 | |
| SCHEMBL14397805 | 0.81 | SMN1; SMN2 (0.58) | ALDH1A1HPGDKDM4EPOLBMEN1 | |
| SCHEMBL8211021 | 0.81 | ALDH1A1 (0.55) | HDAC4HDAC2HDAC8CYP2D6CYP2C9 | |
| SCHEMBL16107035 | 0.80 | SMN1; SMN2 (0.53) | HPGDKDM4EPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070060573-A1 | Acyltryptophanols | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070060573-A1 | Acyltryptophanols | FSHR, NPY1R, NPY2R | HDAC4 2582/4885HDAC2 1250/4885HDAC8 1575/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.