Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 1/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.33 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13862190 | 0.88 | CFD (0.35) | METTL3PCSK9 | |
| SCHEMBL1045267 | 0.88 | METTL3 (0.44) | METTL3 | |
| SCHEMBL11956944 | 0.87 | SLC22A12 (0.36) | METTL3SLC22A12PCSK9PKMP2RX7 | |
| SCHEMBL3241137 | 0.86 | METTL3 (0.40) | METTL3PCSK9P2RX7 | |
| SCHEMBL11956461 | 0.85 | METTL3 (0.34) | METTL3SLC22A12PCSK9PKMP2RX7 | |
| SCHEMBL11956884 | 0.81 | MAPT (0.37) | SLC22A12PKMP2RX7 | |
| SCHEMBL1044601 | 0.80 | METTL3 (0.43) | METTL3 | |
| SCHEMBL3235225 | 0.78 | METTL3 (0.39) | METTL3 | |
| SCHEMBL14611459 | 0.78 | KDM4E (0.38) | METTL3 | |
| SCHEMBL13862191 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8232401-B2 | Useful as an anti-HIV agent that particularly shows an anti-HIV action based on an integrase inhibitory activity; for treatment or prophylaxis of AIDS; for example, 6-(2,3-dichlorobenzyl)-1-(2-hydroxyethyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid | JAPAN TOBACCO INC. (JP) | 2012-07-31 | — | — | US | disclosed |