Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CDA | P32320 | 2/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14244119 | 0.73 | — | — | |
| SCHEMBL17599191 | 0.70 | — | — | |
| SCHEMBL20796771 | 0.70 | MAPK1 (0.35) | ALDH1A1KDM4EPOLBCDAHSD11B1 | |
| SCHEMBL17138583 | 0.70 | KDM4E (0.39) | ALDH1A1KDM4ECDAHSD11B1 | |
| SCHEMBL9202125 | 0.70 | KDM4E (0.39) | ALDH1A1KDM4EPOLBHSD11B1 | |
| SCHEMBL726957 | 0.68 | HTR2C (0.40) | ALDH1A1KDM4EHSD11B1 | |
| SCHEMBL16058686 | 0.68 | HSD11B1 (0.35) | ALDH1A1KDM4EPOLBCDAHSD11B1 | |
| SCHEMBL3093245 | 0.68 | PDE7A (0.41) | ALDH1A1KDM4EPOLBHSD11B1 | |
| SCHEMBL16199876 | 0.68 | ALDH1A1 (0.42) | ALDH1A1KDM4E | |
| SCHEMBL10807373 | 0.67 | TGM2 (0.34) | ALDH1A1KDM4EHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120058996-A1 | CARBAZOLE CARBOXAMIDE COMPOUNDS USEFUL AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2012-03-08 | — | — | US | claimed |
| US-20120058996-A1 | CARBAZOLE CARBOXAMIDE COMPOUNDS USEFUL AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120058996-A1 | CARBAZOLE CARBOXAMIDE COMPOUNDS USEFUL AS KINASE INHIBITORS | BTK, FLT3, JAK1 | ALDH1A1 3832/4885KDM4E 733/4885POLB 3512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.