Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | SHBG | P04278 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28273166 | 0.79 | ESR1 (0.42) | ESR1ESR2SHBGTAAR1APP | |
| SCHEMBL45199 | 0.79 | MEN1 (0.41) | ESR1ESR2TSHRMEN1KMT2A | |
| SCHEMBL7389 | 0.77 | APP (0.44) | ESR1ESR2APPTSHRMEN1 | |
| SCHEMBL6680416 | 0.75 | TAAR1 (0.58) | ESR1ESR2TAAR1TSHRMAPT | |
| SCHEMBL8326684 | 0.73 | TAAR1 (0.56) | ESR1ESR2TAAR1TSHRMAPT | |
| SCHEMBL10541114 | 0.72 | SHBG (0.50) | ESR1ESR2SHBGTAAR1TP53 | |
| SCHEMBL22317811 | 0.71 | HDAC8 (0.42) | TAAR1MAPTRAB9A | |
| SCHEMBL16035570 | 0.71 | TAAR1 (0.33) | ESR1ESR2SHBGTAAR1 | |
| SCHEMBL9785061 | 0.71 | KIF11 (0.44) | ESR1ESR2TSHRNPC1RAB9A | |
| SCHEMBL13704994 | 0.71 | TSHR (0.55) | TP53TSHRNPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7176269-B2 | Curable composition and its use | MITSUI CHEMICALS, INC. (JP) | 2007-02-13 | — | — | US | disclosed |