Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 3/20 | 0.56 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1541991 | 0.86 | ERN1 (0.64) | ERN1GAAKDM4EALDH1A1PTGS2 | |
| SCHEMBL16707203 | 0.86 | ERN1 (0.51) | ERN1MAP3K14EGFRGAAKDM4E | |
| SCHEMBL9332746 | 0.80 | ERN1 (0.58) | ERN1EGFRGAAKDM4EALDH1A1 | |
| SCHEMBL1182540 | 0.78 | CA1 (0.58) | ERN1GAAKDM4EALDH1A1PTGS2 | |
| SCHEMBL11425977 | 0.77 | MAP3K14 (0.46) | ERN1MAP3K14GAAKDM4EMAPT | |
| SCHEMBL684396 | 0.77 | ALOX5 (0.59) | ERN1EGFRGAAPTGS2ALOX5 | |
| SCHEMBL678214 | 0.77 | ERN1 (0.57) | ERN1EGFRGAAKDM4EALDH1A1 | |
| SCHEMBL17744292 | 0.77 | ERN1 (0.55) | ERN1GAAKDM4EALDH1A1PTGS2 | |
| SCHEMBL14189350 | 0.76 | ACHE (0.50) | ERN1MAP3K14GAAKDM4EALDH1A1 | |
| SCHEMBL11581623 | 0.76 | ABL1 (0.52) | ERN1EGFRALDH1A1PTGS2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070032525-A1 | Piperidine derivatives having ccr3 antagonism | TEIJIN LIMITED, A JAPANESE BODY CORPORATE (JP) | 2007-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070032525-A1 | Piperidine derivatives having ccr3 antagonism | CCR3, CCR1, CCR4 | ERN1 3358/4885MAP3K14 2652/4885EGFR 2846/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.