Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.57 |
| ▸ | ACHE | P22303 | 2/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | MPI | P34949 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL562147 | 0.87 | ERN1 (0.63) | ERN1ACHEGAAMAPTALDH1A1 | |
| SCHEMBL16024748 | 0.87 | ERN1 (0.50) | ERN1ACHEEGFRGAAMAPT | |
| SCHEMBL10053939 | 0.83 | SELL (0.62) | ERN1ACHEEGFRGAAMAPT | |
| SCHEMBL18998295 | 0.82 | ERN1 (0.46) | ERN1ACHEGAAMAPTALDH1A1 | |
| SCHEMBL7520392 | 0.81 | ERN1 (0.57) | ERN1ACHEGAAMAPTALDH1A1 | |
| SCHEMBL684396 | 0.81 | ALOX5 (0.59) | ERN1EGFRGAAMAPTLMNA | |
| SCHEMBL11581623 | 0.79 | ABL1 (0.52) | ERN1EGFRALDH1A1LMNAPTPN1 | |
| SCHEMBL16707206 | 0.79 | ERN1 (0.42) | ERN1ACHEEGFRGAAMAPT | |
| SCHEMBL16362239 | 0.79 | AKR1B1 (0.61) | EGFRGAAMAPTKDM4EPTPN1 | |
| SCHEMBL11330721 | 0.77 | EGFR (0.46) | ERN1EGFRGAAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210155791-A1 | SULFONATED MODIFIERS FOR FROTH FLOTATION | ECOLAB USA INC. | 2021-05-27 | — | — | US | disclosed |
| CN-112079697-A | Preparation method of 5-methyl vanillin | 上海应用技术大学 | 2020-12-15 | — | — | CN | disclosed |
| CN-105142605-B | 1, 2-alkane polyol-containing composition | 大阪有机化学工业株式会社 | 2018-06-08 | — | — | CN | disclosed |
| US-9882137-B2 | Organic semiconductor composition, organic thin film transistor, electronic paper, and display device | FUJIFILM CORPORATION (JP) | 2018-01-30 | — | — | US | disclosed |
| US-9795549-B2 | 1,2-alkane polyol-containing composition | OSAKA ORGANIC CHEMICAL INDUSTRY LTD. (JP) | 2017-10-24 | — | — | US | disclosed |
| WO-2017174206-A1 | SULFONATED AROMATIC COMPOUNDS | CMBLU PROJEKT AG (DE) | 2017-10-12 | — | — | WO | disclosed |
| WO-2017174098-A1 | METHOD FOR PRODUCING LOW MOLECULAR WEIGHT AROMATIC LIGNIN-DERIVED COMPOUNDS | CMBLU PROJEKT AG (DE) | 2017-10-12 | — | — | WO | disclosed |
| US-9738605-B2 | Hybrid compounds of curcumin and melatonin as neuroprotectants for neurodegenerative disorders | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2017-08-22 | — | — | US | disclosed |
| US-20170179387-A1 | ORGANIC SEMICONDUCTOR COMPOSITION, ORGANIC THIN FILM TRANSISTOR, ELECTRONIC PAPER, AND DISPLAY DEVICE | FUJIFILM CORPORATION (JP) | 2017-06-22 | — | — | US | disclosed |
| US-20160045414-A1 | 1,2-ALKANE POLYOL-CONTAINING COMPOSITION | OSAKA ORGANIC CHEMICAL INDUSTRY LTD. (JP) | 2016-02-18 | — | — | US | disclosed |
| US-20110124832-A1 | NOVEL LIVING RADICAL POLYMERIZATION METHOD USING ALCOHOL AS CATALYST | KYOTO UNIVERSITY (JP) | 2011-05-26 | — | — | US | disclosed |
| US-7897603-B2 | Selected CGRP-antagonists, processes for preparing them and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-03-01 | — | — | US | disclosed |
| US-20090253680-A1 | SELECTED CGRP-ANTAGONISTS, PROCESSES FOR PREPARING THEM AND THEIR USE AS PHARMACEUTICAL COMPOSITIONS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-10-08 | — | — | US | disclosed |
| US-20090203653-A1 | Compositions and Methods Using Apocynin Compounds and Nitric Oxide Donors | NITROMED, INC. (US) | 2009-08-13 | — | — | US | disclosed |
| US-7528129-B2 | CGRP-antagonists, process for preparing them and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-05-05 | — | — | US | disclosed |
| US-7455948-B2 | Photosensitive resin composition | TORAY INDUSTRIES, INC. (JP) | 2008-11-25 | — | — | US | disclosed |
| WO-2008071587-A2 | 2-(PIPERIDIN-4-YL)-4-PHENOXY- OR PHENYLAMINO-PYRIMIDINE DERIVATIVES AS NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2008-06-19 | — | — | WO | disclosed |
| US-7208481-B2 | Aminodiphosphonate apolipoprotein E modulators | ILEX PRODUCTS, INC. (US) | 2007-04-24 | — | — | US | disclosed |
| US-7208481-B2 | Aminodiphosphonate apolipoprotein E modulators | ILEX PRODUCTS, INC. (US) | 2007-04-24 | — | — | US | disclosed |
| EP-1770091-A1 | CGRP-antagonists, process for their preparation as well as their use as medicaments | Boehringer Ingelheim Pharma GmbH & Co. KG (DE) | 2007-04-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090253680-A1 | SELECTED CGRP-ANTAGONISTS, PROCESSES FOR PREPARING THEM AND THEIR USE AS PHARMACEUTICAL COMPOSITIONS | CALCRL, CALCR, BDKRB2 | ERN1 3283/4885ACHE 812/4885EGFR 2375/4885 |
| US-20110124832-A1 | NOVEL LIVING RADICAL POLYMERIZATION METHOD USING ALCOHOL AS CATALYST | ADH5, ADH1A, ADH1C | ERN1 2198/4885ACHE 1841/4885EGFR 3642/4885 |
| US-20090203653-A1 | Compositions and Methods Using Apocynin Compounds and Nitric Oxide Donors | NOX4, NOS2, REN | ERN1 2604/4885ACHE 941/4885EGFR 2449/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.