Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 4/20 | 0.41 |
| ▸ | NMBR | P28336 | 2/20 | 0.40 |
| ▸ | CASP3 | P42574 | 4/20 | 0.39 |
| ▸ | MDM4 | O15151 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28015870 | 0.79 | MDM4 (0.56) | CASP3MDM4TP53 | |
| SCHEMBL20677239 | 0.79 | MDM4 (0.56) | CASP3MDM4TP53 | |
| SCHEMBL17269327 | 0.79 | MDM4 (0.56) | CASP3MDM4TP53 | |
| SCHEMBL30600490 | 0.79 | MDM4 (0.56) | CASP3MDM4TP53 | |
| SCHEMBL20106639 | 0.79 | MDM4 (0.47) | RENCASP3MDM4TP53 | |
| SCHEMBL15164253 | 0.75 | MDM4 (0.48) | CASP3MDM4TP53 | |
| SCHEMBL27890071 | 0.74 | MDM4 (0.49) | CASP3MDM4TP53 | |
| SCHEMBL17269328 | 0.71 | MDM4 (0.47) | MDM4TP53 | |
| SCHEMBL30645084 | 0.68 | PTPN1 (0.53) | CASP3MDM4TP53PTPN1 | |
| SCHEMBL31589788 | 0.68 | PTPN1 (0.56) | CASP3MDM4TP53PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070027303-A1 | Metal chelate complexes immobilized on solid supports for peptide preparation | APLAGEN GMBH (DE) | 2007-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070027303-A1 | Metal chelate complexes immobilized on solid supports for peptide preparation | SPR, RPS27A, CDC37 | REN 1987/4885NMBR 1595/4885CASP3 4452/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.