Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.43 |
| ▸ | TUBB | P07437 | 3/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.43 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14157784 | 0.87 | PTGS2 (0.58) | MAOBHTR7HTR1APTGS2KDM4E | |
| SCHEMBL4116736 | 0.82 | MAOB (0.48) | MAOBHTR7HTR1APTGS2KDM4E | |
| SCHEMBL786754 | 0.82 | PRKCI (0.49) | MAOBPTGS2KDM4EALDH1A1ERN1 | |
| SCHEMBL196298 | 0.80 | CTSS (0.51) | HTR7 | |
| SCHEMBL30777855 | 0.80 | CTSS (0.51) | HTR7 | |
| SCHEMBL24005570 | 0.78 | CTSS (0.50) | HTR7PTGS2 | |
| SCHEMBL14382711 | 0.78 | BACE1 (0.58) | MAOB | |
| SCHEMBL12881923 | 0.77 | HTR7 (0.71) | HTR7HTR1AHTR2AHTR2B | |
| SCHEMBL5681800 | 0.77 | DRD4 (0.62) | HTR7KDM4EALDH1A1 | |
| SCHEMBL2500546 | 0.77 | PTGS2 (0.68) | PTGS2KDM4EALDH1A1SMN1; SMN2TUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1757591-A1 | CINNAMIDE COMPOUND | Eisai R&D Management Co., Ltd. (JP) | 2007-02-28 | — | — | EP | disclosed |