Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.41 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | LGMN | Q99538 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14614586 | 1.00 | MAPT (0.48) | MAPTSMN1; SMN2GAAMAPK1ALDH3A1 | |
| SCHEMBL12891873 | 0.83 | MAPK1 (0.46) | MAPTSMN1; SMN2GAAMAPK1ALDH3A1 | |
| SCHEMBL12891874 | 0.83 | MAPK1 (0.46) | MAPTSMN1; SMN2GAAMAPK1ALDH3A1 | |
| SCHEMBL12993075 | 0.83 | MAPK1 (0.46) | MAPTSMN1; SMN2GAAMAPK1ALDH3A1 | |
| SCHEMBL1240477 | 0.83 | ALDH1A1 (0.42) | MAPTSMN1; SMN2GAAMAPK1KDM4E | |
| SCHEMBL11575622 | 0.74 | HTR2A (0.43) | CYP2D6 | |
| SCHEMBL1240327 | 0.74 | LGMN (0.46) | MAPTSMN1; SMN2KDM4ETSHRALDH1A1 | |
| SCHEMBL30458638 | 0.70 | MAPT (0.66) | MAPTSMN1; SMN2GAAMAPK1ALDH3A1 | |
| SCHEMBL17651382 | 0.70 | MAPT (0.66) | MAPTSMN1; SMN2GAAMAPK1ALDH3A1 | |
| SCHEMBL8264098 | 0.69 | MAPK1 (0.53) | MAPTSMN1; SMN2GAAMAPK1ALDH3A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1757591-A1 | CINNAMIDE COMPOUND | Eisai R&D Management Co., Ltd. (JP) | 2007-02-28 | — | — | EP | disclosed |