SCHEMBL1461472

SCHEMBL1461472

CCCC[PH](CCCC)(CCCC)CCC(C)C

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.35
LMNA P02545 2/20 0.32
DNM1 Q05193 1/20 0.31
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11388396 0.92 OPRM1 (0.39) OPRM1LMNADNM1TSHR
SCHEMBL14252085 0.84 LMNA (0.52) LMNA
SCHEMBL17005689 0.83 LMNA (0.35) LMNA
SCHEMBL51248 0.80 TSHR (0.46) LMNADNM1TSHR
SCHEMBL9849545 0.79 LMNA (0.30) LMNATSHR
SCHEMBL16594197 0.77 LMNA (0.45) LMNA
Fluoride SCHEMBL2114927 0.76 TSHR (0.43) LMNADNM1TSHR
Bromide SCHEMBL2551829 0.76 TSHR (0.43) LMNADNM1TSHR
Butane SCHEMBL16949835 0.76 TSHR (0.43) LMNADNM1TSHR
Fluoride SCHEMBL3413397 0.76 TSHR (0.43) LMNADNM1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0073107-B1 LIQUID SALT EXTRACTION OF AROMATICS FROM PROCESS FEED STREAMS EXXON RESEARCH AND ENGINEERING COMPANY (US) 1985-06-05 EP claimed
US-4359596-A USING QUATERNARY AMMONIUM OR PHOSPHONIUM OR ARSONIUM SALTS EXXON RESEARCH AND ENGINEERING CO. (US) 1982-11-16 US claimed
WO-2011026972-A1 PROCESS FOR THE REMOVAL OF AROMATIC COMPOUNDS FROM A MIXTURE SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2011-03-10 WO disclosed
EP-0073107-B1 LIQUID SALT EXTRACTION OF AROMATICS FROM PROCESS FEED STREAMS EXXON RESEARCH AND ENGINEERING COMPANY (US) 1985-06-05 EP disclosed
EP-0073107-A1 Liquid salt extraction of aromatics from process feed streams EXXON RESEARCH AND ENGINEERING COMPANY (US) 1983-03-02 EP disclosed
US-4359596-A USING QUATERNARY AMMONIUM OR PHOSPHONIUM OR ARSONIUM SALTS EXXON RESEARCH AND ENGINEERING CO. (US) 1982-11-16 US disclosed