Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 4/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21593836 | 0.86 | NPC1 (0.42) | PDE3BPDE3AMAOANPC1ALDH1A1 | |
| SCHEMBL7473916 | 0.82 | MAOA (0.44) | PDE3BPDE3AMAOANPC1ALDH1A1 | |
| SCHEMBL4022214 | 0.82 | NCF1 (0.46) | PDE3BPDE3AMAOANPC1ALDH1A1 | |
| SCHEMBL21444532 | 0.81 | ALDH1A1 (0.41) | NPC1ALDH1A1TRPV1SMN1; SMN2MEN1 | |
| SCHEMBL22996784 | 0.79 | PDE3B (0.46) | PDE3BPDE3AMAOAALDH1A1SMN1; SMN2 | |
| SCHEMBL22242835 | 0.79 | MAOA (0.40) | PDE3BPDE3AMAOANPC1ALDH1A1 | |
| SCHEMBL24451262 | 0.79 | HTR2C (0.47) | ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL7812585 | 0.78 | NPC1 (0.57) | PDE3BPDE3ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL12831239 | 0.76 | KDM4E (0.44) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL18879756 | 0.76 | HRH3 (0.47) | ALDH1A1SMN1; SMN2CYP2A13MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1757591-A1 | CINNAMIDE COMPOUND | Eisai R&D Management Co., Ltd. (JP) | 2007-02-28 | — | — | EP | disclosed |