Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14615372 | 0.81 | KAT2B (0.35) | ALOX5KCNH2HDAC1HDAC2KAT2B | |
| SCHEMBL14615110 | 0.72 | ALOX5 (0.34) | ALOX5KCNH2 | |
| SCHEMBL14615042 | 0.71 | ADORA2A (0.38) | — | |
| SCHEMBL15478165 | 0.67 | PTPN1 (0.44) | KAT2B | |
| SCHEMBL16639002 | 0.66 | TAAR1 (0.45) | HDAC1HDAC2KAT2B | |
| SCHEMBL18779297 | 0.64 | HDAC1 (0.45) | HDAC1HDAC2KAT2B | |
| SCHEMBL28059752 | 0.63 | KAT2B (0.38) | HDAC1HDAC2KAT2B | |
| SCHEMBL18779296 | 0.63 | HDAC1 (0.37) | HDAC1HDAC2KAT2B | |
| SCHEMBL15692626 | 0.63 | ASIC3 (0.45) | HDAC1HDAC2KAT2B | |
| SCHEMBL15478163 | 0.63 | PTPN1 (0.36) | ALOX5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007016784-A1 | NOVEL SUBSTITUTED 1,2,3-TΠAZOLYLMETHYL-BENZOTHIOPHENE OR -INDOLE AND THEIR USE AS LEUKOTΠENE BIOSYNTHESIS INHIBITORS | MERCK FROSST CANADA LTD. (CA) | 2007-02-15 | — | — | WO | disclosed |