Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PRNP | P04156 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.33 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | FER | P16591 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13694599 | 0.78 | L3MBTL1 (0.47) | ALDH1A1DPP4MAPK1MAPTPRNP | |
| SCHEMBL14615109 | 0.73 | CYP2A6 (0.36) | ALDH1A1DPP4MAPK1MAPTPRNP | |
| SCHEMBL14615049 | 0.73 | CYP2C9 (0.44) | ALDH1A1MAPTPRNPPPARGRXFP1 | |
| SCHEMBL14615112 | 0.72 | ALOX5 (0.37) | ALOX5KCNH2 | |
| SCHEMBL14615044 | 0.71 | ALDH1A1 (0.40) | ALDH1A1MAPTPRNPPPARGRXFP1 | |
| SCHEMBL19010448 | 0.70 | ALDH1A1 (0.50) | ALOX5ALDH1A1MAPK1MAPTPRNP | |
| Hydrochloric Acid SCHEMBL11624757 | 0.70 | DPP4 (0.40) | ALDH1A1DPP4MAPTPRNPPPARG | |
| SCHEMBL17037088 | 0.68 | LIMK1 (0.49) | ALDH1A1MAPK1MAPTNPC1RAB9A | |
| SCHEMBL14615113 | 0.68 | ALDH1A1 (0.49) | ALOX5KCNH2ALDH1A1MAPK1MAPT | |
| SCHEMBL824275 | 0.67 | ALDH1A1 (0.48) | ALDH1A1DPP4MAPK1MAPTPRNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007016784-A1 | NOVEL SUBSTITUTED 1,2,3-TΠAZOLYLMETHYL-BENZOTHIOPHENE OR -INDOLE AND THEIR USE AS LEUKOTΠENE BIOSYNTHESIS INHIBITORS | MERCK FROSST CANADA LTD. (CA) | 2007-02-15 | — | — | WO | disclosed |