Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 8/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | ELANE | P08246 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 7/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3429599 | 0.76 | HTR6 (0.65) | HTR6MAPTALDH1A1HPGDTDP1 | |
| SCHEMBL3426938 | 0.72 | HTR6 (0.59) | HTR6MAPTALDH1A1CA9CA2 | |
| SCHEMBL4049883 | 0.71 | HTR6 (0.46) | HTR6MAPTALDH1A1KDM4E | |
| SCHEMBL4049266 | 0.71 | HTR6 (0.46) | HTR6MAPTALDH1A1KDM4E | |
| SCHEMBL14177901 | 0.71 | HTR6 (0.46) | HTR6MAPTALDH1A1KDM4E | |
| SCHEMBL14732436 | 0.71 | HTR6 (0.46) | HTR6MAPTALDH1A1HPGDCA9 | |
| SCHEMBL4053320 | 0.69 | HTR6 (0.46) | HTR6MAPTALDH1A1HPGDCA9 | |
| SCHEMBL4057157 | 0.69 | HTR6 (0.46) | HTR6MAPTALDH1A1HPGDCA9 | |
| SCHEMBL28393409 | 0.66 | RAB9A (0.49) | MAPTALDH1A1HPGDNPSR1KDM4E | |
| SCHEMBL4047382 | 0.66 | HTR6 (0.45) | HTR6MAPTALDH1A1HPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1581538-B1 | TETRACYCLIC 3-SUBSTITUTED INDOLES HAVING SEROTONIN RECEPTOR AFFINITY | SUVEN LIFE SCIENCES LTD (IN) | 2007-02-28 | — | — | EP | disclosed |