Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | LMNA | P02545 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | TOP2A | P11388 | 2/20 | 0.53 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | CASP9 | P55211 | 1/20 | 0.42 |
| ▸ | BAX | Q07812 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5563659 | 1.00 | ALDH1A1 (0.53) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL5563664 | 1.00 | ALDH1A1 (0.53) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL14585961 | 0.86 | KDM4E (0.51) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL1915366 | 0.82 | ALDH1A1 (0.61) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL8881120 | 0.82 | ALDH1A1 (0.55) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL30615686 | 0.82 | ALDH1A1 (0.61) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| Bicarbonate SCHEMBL10873564 | 0.79 | KDM4E (0.66) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL21724509 | 0.74 | KDM4E (0.69) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL8572108 | 0.71 | KDM4E (0.71) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL10700098 | 0.70 | KDM4E (0.69) | ALDH1A1KDM4ELMNAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7176206-B2 | Antibiotics | DAR AL DAWA DEVELOPMENT AND INVESTMENT CO. (JO) | 2007-02-13 | — | — | US | disclosed |