Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.61 |
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | HPGD | P15428 | 4/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.61 |
| ▸ | TOP2A | P11388 | 2/20 | 0.61 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | CASP9 | P55211 | 1/20 | 0.45 |
| ▸ | BAX | Q07812 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1915366 | 1.00 | ALDH1A1 (0.61) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| Bicarbonate SCHEMBL10873564 | 0.95 | KDM4E (0.66) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL10655744 | 0.86 | KDM4E (0.47) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL8881120 | 0.85 | ALDH1A1 (0.55) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL14585956 | 0.85 | ALDH1A1 (0.48) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL20286630 | 0.85 | KCNH2 (0.48) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL5563659 | 0.82 | ALDH1A1 (0.53) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL14615699 | 0.82 | ALDH1A1 (0.53) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL5563664 | 0.82 | ALDH1A1 (0.53) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL5566403 | 0.82 | KDM4E (0.43) | ALDH1A1KDM4ELMNAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117338732-A | Ciprofloxacin hydrochloride freeze-dried powder injection for injection and preparation method thereof | 海南久常制药有限公司 | 2024-01-05 | — | — | CN | disclosed |
| CN-112824390-B | Acrylic ketone derivative of ciprofloxacin and preparation method and application thereof | 河南大学 | 2023-08-11 | — | — | CN | disclosed |