Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.61 |
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | HPGD | P15428 | 4/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.61 |
| ▸ | TOP2A | P11388 | 2/20 | 0.61 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | CASP9 | P55211 | 1/20 | 0.45 |
| ▸ | BAX | Q07812 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30615686 | 1.00 | ALDH1A1 (0.61) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| Bicarbonate SCHEMBL10873564 | 0.95 | KDM4E (0.66) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL10655744 | 0.86 | KDM4E (0.47) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL8881120 | 0.85 | ALDH1A1 (0.55) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL14585956 | 0.85 | ALDH1A1 (0.48) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL20286630 | 0.85 | KCNH2 (0.48) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL5563659 | 0.82 | ALDH1A1 (0.53) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL14615699 | 0.82 | ALDH1A1 (0.53) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL5563664 | 0.82 | ALDH1A1 (0.53) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL5566403 | 0.82 | KDM4E (0.43) | ALDH1A1KDM4ELMNAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0169993-B1 | 7-(3-ARYL-1-PIPERAZINYL) AND 7-(3-CYCLOHEXYL-1-PIPERAZINYL) 3-QUINOLINE CARBOXYLIC ACIDS | BAYER AG (DE) | 1988-12-28 | — | — | EP | claimed |
| CN-112824390-B | Acrylic ketone derivative of ciprofloxacin and preparation method and application thereof | 河南大学 | 2023-08-11 | — | — | CN | disclosed |
| US-8753875-B2 | Compositions and means for diagnosing microbial infections | STATENS SERUM INSTITUT (DK) | 2014-06-17 | — | — | US | disclosed |
| US-20140073631-A1 | ANTIVIRAL AND ANTIMICROBIAL COMPOUNDS | VYMED CORPORATION (US) | 2014-03-13 | — | — | US | disclosed |
| EP-2515907-A1 | FLUOROQUINOLONES FOR THE TREATMENT AND/OR PROPHYLAXIS OF INFLAMMATORY DISEASES | Deutsches Krebsforschungszentrum (DE) | 2012-10-31 | — | — | EP | disclosed |
| WO-2012127505-A3 | IMPROVED PROCESS FOR THE PREPARATION OF CIPROFLOXACIN AND ITS ACID ADDITION SALTS | DAVULURI RAMAMOHAN RAO (IN) | 2012-10-18 | — | — | WO | disclosed |
| WO-2012127505-A2 | IMPROVED PROCESS FOR THE PREPARATION OF CIPROFLOXACIN AND ITS ACID ADDITION SALTS | DAVULURI RAMAMOHAN RAO (IN) | 2012-09-27 | — | — | WO | disclosed |
| WO-2011076721-A1 | FLUOROQUINOLONES FOR THE TREATMENT AND/OR PROPHYLAXIS OF INFLAMMATORY DISEASES | DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) | 2011-06-30 | — | — | WO | disclosed |
| CN-101699292-A | Rabbit monoclonal antibody based ciprofloxacin residue analysis enzyme-linked immune adsorption kit | UNIV ZHEJIANG | 2010-04-28 | — | — | CN | disclosed |
| US-20090068696-A1 | COMPOSITIONS AND MEANS FOR DIAGNOSING MICROBIAL INFECTIONS | STATENS SERUM INSTITUT | 2009-03-12 | — | — | US | disclosed |
| US-7176206-B2 | Antibiotics | DAR AL DAWA DEVELOPMENT AND INVESTMENT CO. (JO) | 2007-02-13 | — | — | US | disclosed |
| CN-1612888-A | Macrolides | GLAXO GROUP LTD (GB) | 2005-05-04 | — | — | CN | disclosed |
| US-20050080025-A1 | Macrolides | PLIVA D.D. (HR) | 2005-04-14 | — | — | US | disclosed |
| EP-1453846-A1 | MACROLIDES | GLAXO GROUP LIMITED (GB) | 2004-09-08 | — | — | EP | disclosed |
| US-20040132740-A1 | Novel antibiotics | DAR AL DAWA DEVELOPMENT AND INVESTMENT CO. (JO) | 2004-07-08 | — | — | US | disclosed |
| EP-1245566-B1 | Quinolin-4-one derivatives and their use as antibiotics | DAR AL DAWA DEV (JO) | 2004-01-07 | — | — | EP | disclosed |
| EP-1373211-A1 | QUINOLINE DERIVATIVES AND THEIR USE AS ANTIBIOTICS | Dar Al Dawa Development, and Investment Co. (JO) | 2004-01-02 | — | — | EP | disclosed |
| WO-2003042228-A1 | MACROLIDES | GLAXO GROUP LIMITED (GB) | 2003-05-22 | — | — | WO | disclosed |
| WO-2002079164-A1 | QUINOLINE DERIVATIVES AND THEIR USE AS ANTIBIOTICS | DAR AL DAWA DEVELOPMENT AND INVESTMENT CO. (JO) | 2002-10-10 | — | — | WO | disclosed |
| EP-1245566-A1 | Quinolin-4-one derivatives and their use as antibiotics | Dar Al Dawa Development, and Investment Co. (JO) | 2002-10-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050080025-A1 | Macrolides | IL17A, CYP51A1, IL15 | ALDH1A1 2889/4885KDM4E 2733/4885LMNA 1397/4885 |
| US-20040132740-A1 | Novel antibiotics | DPM1, KDM5A, KDM5B | ALDH1A1 1584/4885KDM4E 27/4885LMNA 3715/4885 |
| US-20140073631-A1 | ANTIVIRAL AND ANTIMICROBIAL COMPOUNDS | GDA, GMPS, GANC | ALDH1A1 2165/4885KDM4E 2392/4885LMNA 3327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.