Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | SCN1A | P35498 | 1/20 | 0.52 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.52 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.50 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1784136 | 0.91 | TSHR (0.57) | LMNACYP1A2CYP2D6POLBSCN1A | |
| SCHEMBL19872832 | 0.90 | ALDH1A1 (0.51) | LMNACYP1A2CYP2D6POLBSCN1A | |
| SCHEMBL13866351 | 0.88 | ALDH1A1 (0.54) | LMNACYP1A2CYP2D6POLBSCN1A | |
| SCHEMBL13866325 | 0.88 | ALDH1A1 (0.54) | LMNACYP1A2CYP2D6POLBSCN1A | |
| SCHEMBL443825 | 0.86 | ALDH1A1 (0.54) | LMNACYP1A2CYP2D6POLBSCN1A | |
| SCHEMBL525077 | 0.85 | LMNA (0.55) | LMNACYP1A2CYP2D6POLBSCN1A | |
| SCHEMBL1926470 | 0.85 | LMNA (0.55) | LMNACYP1A2CYP2D6POLBSCN1A | |
| SCHEMBL14043459 | 0.85 | TSHR (0.47) | LMNACYP1A2CYP2D6POLBSCN1A | |
| SCHEMBL7620696 | 0.84 | LMNA (0.51) | LMNACYP1A2CYP2D6POLBSCN1A | |
| SCHEMBL8946971 | 0.84 | LMNA (0.51) | LMNACYP1A2CYP2D6POLBSCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070037206-A1 | Polypeptide of given sequence and antibodies that bind; gene expression; treatment of muscular dystrophy and cystic fibrosis | HUMAN GENOME SCIENCES, INC. | 2007-02-15 | — | — | US | disclosed |