SCHEMBL525077

SCHEMBL525077

CC(CO)OC(=O)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.55
CYP1A2 P05177 1/20 0.55
CYP2D6 P10635 1/20 0.55
POLB P06746 1/20 0.55
SCN1A P35498 1/20 0.55
SCN2A Q99250 1/20 0.55
SCN3A Q9NY46 1/20 0.55
TSHR P16473 3/20 0.55
TP53 P04637 1/20 0.55
NPC1 O15118 2/20 0.54
PDCD1 Q15116 1/20 0.53
CD274 Q9NZQ7 1/20 0.53
ALDH1A1 P00352 2/20 0.50
HTT P42858 1/20 0.50
RAB9A P51151 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
PRKCA P17252 1/20 0.49
F2 P00734 1/20 0.48
CYP4F2 P78329 1/20 0.46
CYP4A11 Q02928 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1926470 1.00 LMNA (0.55) LMNACYP1A2CYP2D6POLBSCN1A
SCHEMBL7615892 0.90 CYP4F2 (0.55) LMNACYP1A2CYP2D6POLBSCN1A
SCHEMBL4915922 0.90 PDCD1 (0.70) LMNACYP1A2CYP2D6POLBSCN1A
SCHEMBL17797890 0.88 LMNA (0.49) LMNACYP1A2CYP2D6POLBSCN1A
SCHEMBL855278 0.87 MAPT (0.51) LMNACYP1A2CYP2D6POLBSCN1A
SCHEMBL4336178 0.87 LMNA (0.48) LMNACYP1A2CYP2D6POLBSCN1A
SCHEMBL14690004 0.86 TSHR (0.57) LMNACYP1A2CYP2D6POLBSCN1A
SCHEMBL560828 0.86 TSHR (0.57) LMNACYP1A2CYP2D6POLBSCN1A
SCHEMBL1068955 0.86 TSHR (0.57) LMNACYP1A2CYP2D6POLBSCN1A
SCHEMBL1784136 0.86 TSHR (0.57) LMNACYP1A2CYP2D6POLBSCN1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 157 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108463209-B Nail compositions with end-capped oligomers 露华浓消费品公司 2021-09-17 CN claimed
US-20160000067-A1 FORMULATIONS SYNGENTA LIMITED (GB) 2016-01-07 US claimed
EP-1389084-B1 Nail enamel cosmetic films COTY INC (US) 2013-12-18 EP claimed
EP-2598472-A2 FORMULATIONS Syngenta Limited (GB) 2013-06-05 EP claimed
WO-2012014152-A2 FORMULATIONS SYNGENTA LIMITED (GB) 2012-02-02 WO claimed
EP-1389084-A4 COSMETIC FILMS COTY INC (US) 2008-06-11 EP claimed
EP-1472293-A4 SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFINS, CATALYST COMPRISING THE SAME AND USE THEREOF CHINA PETROLEUM & CHEMICAL (CN) 2008-01-16 EP claimed
US-7011821-B2 Cosmetic films COTY, INC. (US) 2006-03-14 US claimed
US-20050019359-A1 Cosmetic films COTY INC. 2005-01-27 US claimed
EP-1472293-A1 SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFINS, CATALYST COMPRISING THE SAME AND USE THEREOF China Petroleum & Chemical Corporation (CN) 2004-11-03 EP claimed
EP-1389084-A1 COSMETIC FILMS Coty Inc. (US) 2004-02-18 EP claimed
WO-2003068828-A1 SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFINS, CATALYST COMPRISING THE SAME AND USE THEREOF CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2003-08-21 WO claimed
US-20030147838-A1 Cosmetic films OPI PRODUCTS, INC. 2003-08-07 US claimed
US-20030124154-A1 Cosmetic films OPI PRODUCTS, INC. 2003-07-03 US claimed
WO-2002102329-A1 COSMETIC FILMS COTY INC. (US) 2002-12-27 WO claimed
EP-3585851-B1 AIR AND WATER BARRIER ARTICLE INCLUDING INELASTIC POROUS LAYER 3M INNOVATIVE PROPERTIES COMPANY (US) 2026-04-01 EP disclosed
US-12403671-B2 Roll including air and water barrier article and method of using the same 3M INNOVATIVE PROPERTIES COMPANY (US) 2025-09-02 US disclosed
US-20030147838-A1 Cosmetic films OPI PRODUCTS, INC. 2003-08-07 US disclosed
US-20030124154-A1 Cosmetic films OPI PRODUCTS, INC. 2003-07-03 US disclosed
WO-2002102329-A1 COSMETIC FILMS COTY INC. (US) 2002-12-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160000067-A1 FORMULATIONS PRMT1, PRMT5, PRMT3 LMNA 2919/4885CYP1A2 44/4885CYP2D6 95/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.