Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 4/20 | 0.53 |
| ▸ | STIM1 | Q13586 | 3/20 | 0.51 |
| ▸ | ORAI1 | Q96D31 | 3/20 | 0.51 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.50 |
| ▸ | KDM4C | Q9H3R0 | 5/20 | 0.49 |
| ▸ | KDM5A | P29375 | 2/20 | 0.49 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.49 |
| ▸ | KDM6B | O15054 | 2/20 | 0.49 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.49 |
| ▸ | KDM3A | Q9Y4C1 | 2/20 | 0.49 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.48 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.47 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | KDM5C | P41229 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3721276 | 0.85 | KDM4C (0.54) | DHODHKDM4CKDM5AKDM5BKDM6B | |
| SCHEMBL21311114 | 0.84 | STIM1 (0.57) | STIM1ORAI1CYP2C8KDM4CKDM5A | |
| SCHEMBL29482126 | 0.84 | STIM1 (0.57) | STIM1ORAI1CYP2C8KDM4CKDM5A | |
| SCHEMBL30765461 | 0.79 | AKR1C3 (0.64) | DHODHCYP2C8AKR1C3AKR1C2KDM4E | |
| SCHEMBL4254012 | 0.77 | STIM1 (0.62) | STIM1ORAI1KDM4EMRGPRX4 | |
| SCHEMBL28441960 | 0.75 | KDM4C (0.67) | KDM4CKDM5AKDM5BKDM6BKDM2A | |
| SCHEMBL29723246 | 0.75 | KDM4C (0.67) | KDM4CKDM5AKDM5BKDM6BKDM2A | |
| SCHEMBL12132851 | 0.74 | KDM4C (0.69) | KDM4CKDM5AKDM5BKDM6BKDM2A | |
| SCHEMBL3713968 | 0.74 | HDAC6 (0.56) | — | |
| SCHEMBL4498726 | 0.73 | KDM4C (0.64) | KDM4CKDM5AKDM5BKDM6BKDM2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070027193-A1 | Method of identifying inhibitors of DHODH | 4SC AG (DE) | 2007-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070027193-A1 | Method of identifying inhibitors of DHODH | DHODH, SQOR, NDUFA5 | DHODH 1/4885STIM1 1887/4885ORAI1 4553/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.