SCHEMBL146162

SCHEMBL146162

CCCc1cc(N)ccc1N

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKCI P41743 1/20 0.42
MAPT P10636 5/20 0.41
ALDH1A1 P00352 4/20 0.41
GAA P10253 3/20 0.41
POLB P06746 3/20 0.41
CASP1 P29466 2/20 0.41
HTT P42858 2/20 0.41
KDM4E B2RXH2 2/20 0.41
MEN1 O00255 2/20 0.41
USP2 O75604 2/20 0.41
KMT2A Q03164 2/20 0.41
ACHE P22303 1/20 0.41
TP53 P04637 1/20 0.41
CASP7 P55210 1/20 0.41
ATM Q13315 1/20 0.41
SKP2 Q13309 1/20 0.38
TSHR P16473 1/20 0.36
MAPK1 P28482 1/20 0.36
AR P10275 1/20 0.34
TLR8 Q9NR97 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30087007 1.00 PRKCI (0.42) PRKCIMAPTALDH1A1GAAPOLB
SCHEMBL39005 0.87 SKP2 (0.48) PRKCIMAPTALDH1A1GAAPOLB
SCHEMBL30227228 0.87 SKP2 (0.48) PRKCIMAPTALDH1A1GAAPOLB
SCHEMBL10952738 0.85 CASP1 (0.40) PRKCIMAPTALDH1A1GAAPOLB
SCHEMBL30227546 0.85 TLR8 (0.44) PRKCIMAPTALDH1A1GAAPOLB
SCHEMBL175665 0.85 TLR8 (0.44) PRKCIMAPTALDH1A1GAAPOLB
SCHEMBL4576433 0.84 PRKCI (0.44) PRKCIMAPTALDH1A1GAAPOLB
SCHEMBL207523 0.84 HTR2A (0.46) MAPTALDH1A1GAAHTTKDM4E
SCHEMBL9517841 0.84 TDP1 (0.42) MAPTALDH1A1POLBKDM4EMEN1
SCHEMBL10345219 0.84 HTR2A (0.46) MAPTALDH1A1GAAHTTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 809 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111971119-B Heterogeneous catalyst for carbamate synthesis 科思创知识产权两合公司 2023-12-08 CN claimed
CN-116836465-A High-wear-resistance tire material and production process thereof 青岛茂驰橡胶制品有限公司 2023-10-03 CN claimed
CN-115911541-A Solid polymer electrolyte containing ionic liquid and preparation method thereof 中国科学院长春应用化学研究所 2023-04-04 CN claimed
CN-115882059-A In-situ polymerization solid polymer electrolyte and preparation method thereof 中国科学院长春应用化学研究所 2023-03-31 CN claimed
CN-110650944-B Silica-based zinc catalysts, their preparation and use in the alkoxycarbonylation of amines 科思创德国股份有限公司 2022-07-19 CN claimed
CN-105229015-B Zinc cluster compounds and their use as catalysts in the reaction of amines with dialkyl carbonates 科思创德国股份公司 2020-11-03 CN claimed
CN-110650944-A Silica-based zinc catalysts, their preparation and use in the alkoxycarbonylation of amines 科思创德国股份有限公司 2020-01-03 CN claimed
CN-109642175-A Marine diesel steam-cylinder lubrication fluid composition 雪佛龙奥伦耐技术有限责任公司 2019-04-16 CN claimed
CN-104817459-B The method for generating cyclic aliphatic two-and polyamines for Hydrogenated aromatic two-and polyamines 科思创德国股份有限公司 2019-03-08 CN claimed
CN-108945956-A A kind of oil resistant conveyer 浙江耐者胶带有限公司 2018-12-07 CN claimed
EP-0728465-B1 Composition for dyeing keratinous fibers comprising a meta-aminophenol and 6-hydroxyindoline, and dyeing process using such a composition OREAL (FR) 1997-03-19 EP claimed
US-5578087-A Dyeing compositions for keratinous fibres based on para-phenylene-diamines, meta-phenylenediamine and benzimidazole derivatives, and dyeing process employing them L'OREAL (FR) 1996-11-26 US claimed
EP-0591373-B1 META-AMINOPHENOLS, THEIR USE AS COUPLERS FOR OXIDATION DYEING OF KERATINOUS FIBRES, DYE COMPOSITIONS AND METHOD OREAL (FR) 1996-05-22 EP claimed
EP-0578735-B1 NOVEL KERATIN FIBRE DYEING METHOD USING AMINOINDOLES, WITH ACID pH, COMPOSITIONS THEREFOR AND NOVEL AMINOINDOLE COMPOUNDS OREAL (FR) 1996-01-03 EP claimed
US-5478359-A Applying a hair dyes L'OREAL (FR) 1995-12-26 US claimed
EP-0506549-B1 Dyeing composition for keratinous fibers containing oxidation dye precursors and hydroxybenzofurans as couplers and dyeing process making use of such a composition OREAL (FR) 1995-10-18 EP claimed
US-5443596-A Keratinous fiber dyeing compositions and processes utilizing oxidation dye precursors in combination with dimethoxy meta-aminophenol couplers L'OREAL (FR) 1995-08-22 US claimed
EP-0580713-B1 METHOD FOR DYEING KERATIN FIBRES WITH AMINOINDOLES HAVING ALKALINE pH, AND COMPOSITIONS THEREFOR OREAL (FR) 1995-03-01 EP claimed
US-5203875-A Hair dyes also using ortho- and para-phenylenediamines or aminophenols; colorfastness; washfastness; perspiration resistance L'OREAL (FR) 1993-04-20 US claimed
EP-0146350-A2 Hair treatment composition UNILEVER PLC (GB) 1985-06-26 EP claimed