Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5380955 | 0.92 | ALDH1A1 (0.45) | TDP1CYP3A4ALDH1A1TP53HSD17B10 | |
| SCHEMBL8076064 | 0.89 | SKP2 (0.43) | TDP1CYP3A4ALDH1A1TP53HSD17B10 | |
| SCHEMBL360103 | 0.87 | ALDH1A1 (0.40) | TDP1CYP3A4ALDH1A1TP53HSD17B10 | |
| SCHEMBL11117161 | 0.86 | MEN1 (0.42) | TDP1CYP3A4ALDH1A1TP53HSD17B10 | |
| SCHEMBL2574764 | 0.84 | ALDH1A1 (0.46) | TDP1CYP3A4ALDH1A1TP53HSD17B10 | |
| SCHEMBL146162 | 0.84 | PRKCI (0.42) | TDP1CYP3A4ALDH1A1TP53MEN1 | |
| SCHEMBL30087007 | 0.84 | PRKCI (0.42) | TDP1CYP3A4ALDH1A1TP53MEN1 | |
| SCHEMBL25885669 | 0.81 | ALDH1A1 (0.38) | TDP1CYP3A4ALDH1A1TP53HSD17B10 | |
| SCHEMBL5377476 | 0.80 | SKP2 (0.48) | TDP1CYP3A4ALDH1A1TP53HSD17B10 | |
| SCHEMBL10424535 | 0.78 | TLR8 (0.44) | TDP1CYP3A4ALDH1A1TP53HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358783-B1 | POLYIMIDE MOLECULAR WEIGHT ENHANCEMENT BY SOLVENT EXTRACTION | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-08-11 | — | — | EP | disclosed |
| EP-0358783-A1 | Polyimide molecular weight enhancement by solvent extraction | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-03-21 | — | — | EP | disclosed |
| US-4906731-A | Polyimide molecular weight enhancement by solvent extraction | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-03-06 | — | — | US | disclosed |