Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 10/20 | 0.49 |
| ▸ | THRA | P10827 | 8/20 | 0.49 |
| ▸ | PCNA | P12004 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.49 |
| ▸ | PPARG | P37231 | 3/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.49 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | RXRA | P19793 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14575001 | 0.91 | THRB (0.54) | THRBTHRAPCNALMNAPOLB | |
| SCHEMBL14575487 | 0.83 | MEN1 (0.58) | THRBTHRAPCNALMNAPOLB | |
| SCHEMBL2784791 | 0.82 | LTA4H (0.54) | THRBTHRAPCNALMNAPOLB | |
| SCHEMBL14616573 | 0.81 | MEN1 (0.61) | PCNAMEN1KMT2ATTR | |
| SCHEMBL9640062 | 0.78 | ALDH1A1 (0.55) | THRBTHRAPCNALMNAPOLB | |
| SCHEMBL9296009 | 0.78 | PPARG (0.40) | THRBTHRAPCNALMNAPPARG | |
| SCHEMBL24407858 | 0.77 | ALDH1A1 (0.50) | THRBTHRAPCNALMNAPOLB | |
| SCHEMBL6567350 | 0.76 | THRB (0.58) | THRBTHRAPCNALMNAPOLB | |
| SCHEMBL18179783 | 0.76 | CYP3A4 (0.47) | THRBTHRALMNAPPARGGABRA1 | |
| SCHEMBL24407712 | 0.76 | THRB (0.54) | THRBTHRAPCNALMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130017163-A1 | HALOGENATED PHENOLS FOR DIAGNOSTICS, ANTIOXIDANT PROTECTION AND DRUG DELIVERY | IPE, INC. | 2013-01-17 | — | — | US | disclosed |
| US-20130017163-A1 | HALOGENATED PHENOLS FOR DIAGNOSTICS, ANTIOXIDANT PROTECTION AND DRUG DELIVERY | IPE, INC. | 2013-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130017163-A1 | HALOGENATED PHENOLS FOR DIAGNOSTICS, ANTIOXIDANT PROTECTION AND DRUG DELIVERY | TYR, PRDX5, PPARG | THRB 3091/4885THRA 2810/4885PCNA 1891/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.