Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Zinc Ion SCHEMBL768293 | 0.95 | ALDH1A1 (0.54) | ALDH1A1TDP1CYP3A4TSHRCA2 | |
| SCHEMBL15462 | 0.95 | ALDH1A1 (0.54) | ALDH1A1TDP1CYP3A4TSHRCA2 | |
| SCHEMBL9417628 | 0.95 | ALDH1A1 (0.54) | ALDH1A1TDP1CYP3A4TSHRCA2 | |
| SCHEMBL1449865 | 0.95 | ALDH1A1 (0.54) | ALDH1A1TDP1CYP3A4TSHRCA2 | |
| SCHEMBL1025105 | 0.95 | ALDH1A1 (0.54) | ALDH1A1TDP1CYP3A4TSHRCA2 | |
| SCHEMBL673226 | 0.95 | ALDH1A1 (0.54) | ALDH1A1TDP1CYP3A4TSHRCA2 | |
| SCHEMBL9417629 | 0.95 | ALDH1A1 (0.54) | ALDH1A1TDP1CYP3A4TSHRCA2 | |
| Potassium Ion SCHEMBL3291106 | 0.95 | ALDH1A1 (0.54) | ALDH1A1TDP1CYP3A4TSHRCA2 | |
| SCHEMBL362089 | 0.95 | ALDH1A1 (0.54) | ALDH1A1TDP1CYP3A4TSHRCA2 | |
| SCHEMBL6064041 | 0.95 | ALDH1A1 (0.54) | ALDH1A1TDP1CYP3A4TSHRCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3688000-B1 | HYDROCARBON-SOLUBLE HALOGEN AND THIOLATE/MAGNESIUM EXCHANGE REAGENTS | ALBEMARLE GERMANY GMBH (DE) | 2023-11-08 | — | — | EP | disclosed |
| US-11236113-B2 | Hydrocarbon-soluble halogen and thiolate/magnesium exchange reagents | ALBEMARLE GERMANY GMBH (DE) | 2022-02-01 | — | — | US | disclosed |
| US-9587060-B2 | Functionalized rubbery polymers | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2017-03-07 | — | — | US | disclosed |
| EP-2475615-A1 | CONTINUOUS SYNTHESIS OF CARBON-COATED LITHIUM-IRON-PHOSPHATE | Clariant International Ltd. (CH) | 2012-07-18 | — | — | EP | disclosed |
| US-20120168686-A1 | Continuous Synthesis of Carbon-Coated Lithium-Iron-Phosphate | CLARIANT FINANCE (BVI) LIMITED (VG) | 2012-07-05 | — | — | US | disclosed |
| WO-2011026581-A1 | CONTINUOUS SYNTHESIS OF CARBON-COATED LITHIUM-IRON-PHOSPHATE | CLARIANT INTERNATIONAL LTD (CH) | 2011-03-10 | — | — | WO | disclosed |
| US-7714089-B2 | Functionalized monomers and functionalized rubbery polymers made therewith | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2010-05-11 | — | — | US | disclosed |
| US-20090156769-A1 | FUNCTIONALIZED MONOMERS AND FUNCTIONALIZED RUBBERY POLYMERS MADE THEREWITH | THE GOODYEAR TIRE & RUBBER COMPANY | 2009-06-18 | — | — | US | disclosed |
| EP-1967531-A1 | Method of making alkoxy functionalized rubbery polymers | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2008-09-10 | — | — | EP | disclosed |
| US-7335706-B1 | Method of making alkoxy functionalized rubbery polymers | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2008-02-26 | — | — | US | disclosed |
| US-20040122194-A1 | Functionalized monomers for synthesis of rubbery polymers | THE GOODYEAR TIRE & RUBBER COMPANY | 2004-06-24 | — | — | US | disclosed |
| US-20040122224-A1 | Functionalized monomers for synthesis of rubbery polymers | THE GOODYEAR TIRE & RUBBER COMPANY | 2004-06-24 | — | — | US | disclosed |
| EP-1036108-B1 | STORAGE-STABLE CATIONICALLY POLYMERISED PREPARATIONS WITH IMPROVED HARDENING CHARACTERISTICS | 3M ESPE AG (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-20040048972-A1 | Functionalized monomers for synthesis of rubbery polymers | GOODYEAR TIRE & RUBBER COMPANY, THE | 2004-03-11 | — | — | US | disclosed |
| US-20040044157-A1 | Functionalized monomers for synthesis of rubbery polymers | GOODYEAR TIRE & RUBBER COMPANY, THE | 2004-03-04 | — | — | US | disclosed |
| US-6599960-B1 | For making dental impressions | ESPE DENTAL AG (DE) | 2003-07-29 | — | — | US | disclosed |
| EP-1213313-A2 | Storage stable cationically polymerisable preparations with improved hardening characteristics | 3M Espe AG (DE) | 2002-06-12 | — | — | EP | disclosed |
| EP-1036108-A2 | STORAGE-STABLE CATIONICALLY POLYMERISED PREPARATIONS WITH IMPROVED HARDENING CHARACTERISTICS | ESPE Dental AG (DE) | 2000-09-20 | — | — | EP | disclosed |
| WO-1999027892-A2 | STORAGE-STABLE CATIONICALLY POLYMERISED PREPARATIONS WITH IMPROVED HARDENING CHARACTERISTICS | ESPE DENTAL AG (DE) | 1999-06-10 | — | — | WO | disclosed |
| US-4113649-A | Method for the solubilizing of alkali metal salts with polyethyleneglycoldiethers and the utilization thereof | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 1978-09-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11236113-B2 | Hydrocarbon-soluble halogen and thiolate/magnesium exchange reagents | MSRB3, OR10J3, GFER | ALDH1A1 2179/4885TDP1 3872/4885CYP3A4 653/4885 |
| US-20040122224-A1 | Functionalized monomers for synthesis of rubbery polymers | PRMT1, DDR2, DNMT3A | ALDH1A1 885/4885TDP1 1387/4885CYP3A4 1759/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.