Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 10/20 | 0.48 |
| ▸ | CDC25B | P30305 | 8/20 | 0.48 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.48 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.48 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.48 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.48 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 5/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 5/20 | 0.47 |
| ▸ | PTPN6 | P29350 | 4/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | GJB2 | P29033 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26447373 | 1.00 | NT5E (0.57) | NT5EPTPN1CDC25BSSTR1SSTR2 | |
| SCHEMBL2804791 | 1.00 | NT5E (0.57) | NT5EPTPN1CDC25BSSTR1SSTR2 | |
| SCHEMBL10259814 | 1.00 | NT5E (0.57) | NT5EPTPN1CDC25BSSTR1SSTR2 | |
| SCHEMBL6895176 | 1.00 | NT5E (0.57) | NT5EPTPN1CDC25BSSTR1SSTR2 | |
| SCHEMBL2989107 | 1.00 | NT5E (0.57) | NT5EPTPN1CDC25BSSTR1SSTR2 | |
| SCHEMBL19204220 | 1.00 | NT5E (0.57) | NT5EPTPN1CDC25BSSTR1SSTR2 | |
| SCHEMBL6574752 | 1.00 | NT5E (0.57) | NT5EPTPN1CDC25BSSTR1SSTR2 | |
| SCHEMBL13129824 | 1.00 | NT5E (0.57) | NT5EPTPN1CDC25BSSTR1SSTR2 | |
| SCHEMBL15975379 | 1.00 | NT5E (0.57) | NT5EPTPN1CDC25BSSTR1SSTR2 | |
| SCHEMBL2287945 | 1.00 | NT5E (0.57) | NT5EPTPN1CDC25BSSTR1SSTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9181293-B2 | Method for the synthesis of aspalathin and analogues thereof | SOUTH AFRICAN MEDICAL RESEARCH COUNCIL (ZA) | 2015-11-10 | — | — | US | disclosed |
| US-20130018182-A1 | Method for the Synthesis of Aspalathin and Analogues Thereof | SOUTH AFRICAN MEDICAL RESEARCH COUNCIL (ZA) | 2013-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130018182-A1 | Method for the Synthesis of Aspalathin and Analogues Thereof | ASPH, C9, ALDH3A1 | NT5E 3950/4885PTPN1 4207/4885CDC25B 3072/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.