SCHEMBL2989107

SCHEMBL2989107

N=C(O[C@@H]1O[C@H](COCc2ccccc2)[C@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1)C(Cl)(Cl)Cl

nearest known ligand 0.57

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NT5E P21589 1/20 0.57
PTPN1 P18031 10/20 0.48
CDC25B P30305 8/20 0.48
SSTR1 P30872 1/20 0.48
SSTR2 P30874 1/20 0.48
SSTR4 P31391 1/20 0.48
SSTR3 P32745 1/20 0.48
SSTR5 P35346 1/20 0.48
PTPN2 P17706 5/20 0.47
PTPN11 Q06124 5/20 0.47
PTPN6 P29350 4/20 0.47
HTR1A P08908 1/20 0.45
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA9 Q16790 1/20 0.43
GJB2 P29033 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26447373 1.00 NT5E (0.57) NT5EPTPN1CDC25BSSTR1SSTR2
SCHEMBL2804791 1.00 NT5E (0.57) NT5EPTPN1CDC25BSSTR1SSTR2
SCHEMBL10259814 1.00 NT5E (0.57) NT5EPTPN1CDC25BSSTR1SSTR2
SCHEMBL6895176 1.00 NT5E (0.57) NT5EPTPN1CDC25BSSTR1SSTR2
SCHEMBL14616676 1.00 NT5E (0.57) NT5EPTPN1CDC25BSSTR1SSTR2
SCHEMBL19204220 1.00 NT5E (0.57) NT5EPTPN1CDC25BSSTR1SSTR2
SCHEMBL6574752 1.00 NT5E (0.57) NT5EPTPN1CDC25BSSTR1SSTR2
SCHEMBL13129824 1.00 NT5E (0.57) NT5EPTPN1CDC25BSSTR1SSTR2
SCHEMBL15975379 1.00 NT5E (0.57) NT5EPTPN1CDC25BSSTR1SSTR2
SCHEMBL2287945 1.00 NT5E (0.57) NT5EPTPN1CDC25BSSTR1SSTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10919941-B2 Functional lipid constructs KODE BIOTECH LIMITED (NZ) 2021-02-16 US disclosed
US-10858384-B2 Synthetic molecule constructs KODE BIOTECH LIMITED (NZ) 2020-12-08 US disclosed
US-20200123188-A1 SYNTHETIC MOLECULE CONSTRUCTS KODE BIOTECH LIMITED (NZ) 2020-04-23 US disclosed
US-10414786-B2 Synthetic membrane anchors KODE BIOTECH LIMITED (NZ) 2019-09-17 US disclosed
US-20180057518-A1 SYNTHETIC MEMBRANE ANCHORS KODE BIOTECH LTD. (NZ) 2018-03-01 US disclosed
US-20170218027-A1 FUNCTIONAL LIPID CONSTRUCTS KODE BIOTECH LIMITED (NZ) 2017-08-03 US disclosed
US-20160361423-A1 CARBOHYDRATE-LIPID CONSTRUCTS AND THEIR USE IN PREVENTING OR TREATING VIRAL INFECTION KODE BIOTECH LTD (NZ) 2016-12-15 US disclosed
US-9226968-B2 Carbohydrate-lipid constructs and their use in preventing or treating viral infection KODE BIOTECH LIMITED (NZ) 2016-01-05 US disclosed
US-20140200191-A1 CARBOHYDRATE-LIPID CONSTRUCTS AND THEIR USE IN PREVENTING OR TREATING VIRAL INFECTION KODE BIOTECH LIMITED (NZ) 2014-07-17 US disclosed
US-20120277172-A1 CARBOHYDRATE-LIPID CONSTRUCTS AND THEIR USE IN PREVENTING OR TREATING VIRAL INFECTION KODE BIOTECH LIMITED (NZ) 2012-11-01 US disclosed
US-8211860-B2 Carbohydrate-lipid constructs and their use in preventing or treating viral infection KODE BIOTECH LIMITED (NZ) 2012-07-03 US disclosed
US-20100184723-A1 CARBOHYDRATE-LIPID CONSTRUCTS AND THEIR USE IN PREVENTING OR TREATING VIRAL INFECTION KODE BIOTECH LIMITED (NZ) 2010-07-22 US disclosed
EP-0970114-B1 NEOGLYCOPROTEINS NOVARTIS AG (CH) 2006-07-12 EP disclosed
US-6723831-B2 REMOVAL ANTIBODIES FROM BODY FLUIDS NOVARTIS AG (CH) 2004-04-20 US disclosed
US-6399071-B1 Neoglycoproteins NOVARTIS AG (CH) 2002-06-04 US disclosed
EP-0970114-A1 NEOGLYCOPROTEINS Novartis AG (CH) 2000-01-12 EP disclosed
WO-1998047915-A1 NEOGLYCOPROTEINS NOVARTIS AG (CH) 1998-10-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140200191-A1 CARBOHYDRATE-LIPID CONSTRUCTS AND THEIR USE IN PREVENTING OR TREATING VIRAL INFECTION HAVCR2, SIGLEC7, FUT5 NT5E 1700/4885PTPN1 967/4885CDC25B 3462/4885
US-20160361423-A1 CARBOHYDRATE-LIPID CONSTRUCTS AND THEIR USE IN PREVENTING OR TREATING VIRAL INFECTION HAVCR2, SIGLEC7, FUT5 NT5E 1700/4885PTPN1 967/4885CDC25B 3462/4885
US-20170218027-A1 FUNCTIONAL LIPID CONSTRUCTS CETP, LCAT, LIPA NT5E 2160/4885PTPN1 2488/4885CDC25B 4058/4885
US-10919941-B2 Functional lipid constructs CETP, LCAT, LIPA NT5E 2160/4885PTPN1 2488/4885CDC25B 4058/4885
US-20180057518-A1 SYNTHETIC MEMBRANE ANCHORS PTDSS2, DDOST, STT3B NT5E 2691/4885PTPN1 4708/4885CDC25B 1049/4885
US-20100184723-A1 CARBOHYDRATE-LIPID CONSTRUCTS AND THEIR USE IN PREVENTING OR TREATING VIRAL INFECTION HAVCR2, SIGLEC7, CD14 NT5E 1558/4885PTPN1 949/4885CDC25B 3384/4885
US-20200123188-A1 SYNTHETIC MOLECULE CONSTRUCTS PTDSS2, PTDSS1, UGCG NT5E 1938/4885PTPN1 4188/4885CDC25B 2690/4885
US-20120277172-A1 CARBOHYDRATE-LIPID CONSTRUCTS AND THEIR USE IN PREVENTING OR TREATING VIRAL INFECTION HAVCR2, SIGLEC7, FUT5 NT5E 1700/4885PTPN1 967/4885CDC25B 3462/4885
US-10414786-B2 Synthetic membrane anchors PTDSS2, DDOST, STT3B NT5E 2634/4885PTPN1 4704/4885CDC25B 1118/4885
US-10858384-B2 Synthetic molecule constructs PTDSS2, PTDSS1, UGCG NT5E 1942/4885PTPN1 4189/4885CDC25B 2653/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.