Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | IL1B | P01584 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.34 |
| ▸ | LOX | P28300 | 1/20 | 0.34 |
| ▸ | GCK | P35557 | 1/20 | 0.34 |
| ▸ | RRM2 | P31350 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | ITK | Q08881 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14795026 | 0.85 | PTGS2 (0.44) | L3MBTL1IL1BPTGS2CYP4F2CYP4A11 | |
| SCHEMBL4550334 | 0.83 | L3MBTL1 (0.40) | L3MBTL1CYP4F2CYP4A11LOXL2LOX | |
| Hydrochloric Acid SCHEMBL2714396 | 0.82 | L3MBTL1 (0.39) | L3MBTL1CYP4F2CYP4A11LOXL2LOX | |
| SCHEMBL2228010 | 0.79 | KDM4E (0.49) | L3MBTL1IL1BGCKDGAT1EGFR | |
| SCHEMBL3890599 | 0.79 | L3MBTL1 (0.53) | L3MBTL1LOXL2LOXMAPT | |
| SCHEMBL30939139 | 0.79 | L3MBTL1 (0.53) | L3MBTL1LOXL2LOXMAPT | |
| Hydrochloric Acid SCHEMBL2713855 | 0.78 | L3MBTL1 (0.51) | L3MBTL1LOXL2LOXMAPT | |
| Hydrochloric Acid SCHEMBL5012085 | 0.78 | L3MBTL1 (0.51) | L3MBTL1LOXL2LOXMAPT | |
| SCHEMBL20133299 | 0.77 | LOXL2 (0.37) | CYP4F2CYP4A11LOXL2LOXRRM2 | |
| SCHEMBL17339971 | 0.77 | KDM4E (0.45) | L3MBTL1IL1BPTGS2GCKDGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120238533-A1 | (Heteroarylmethyl) Thiohydantoins as anticancer drugs | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-09-20 | — | — | US | disclosed |
| EP-2475366-A1 | SUBSTITUTED (HETEROARYLMETHYL) THIOHYDANTOINS AS ANTICANCER DRUGS | Bayer Pharma Aktiengesellschaft (DE) | 2012-07-18 | — | — | EP | disclosed |
| WO-2011029782-A1 | SUBSTITUTED (HETEROARYLMETHYL) THIOHYDANTOINS AS ANTICANCER DRUGS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2011-03-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120238533-A1 | (Heteroarylmethyl) Thiohydantoins as anticancer drugs | SRD5A1, NR5A1, SRD5A2 | L3MBTL1 1912/4885IL1B 2715/4885PTGS2 1268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.