Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GABBR2 | O75899 | 2/20 | 0.32 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.30 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19090256 | 0.85 | — | — | |
| SCHEMBL22527 | 0.85 | — | — | |
| SCHEMBL13528424 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL23174946 | 0.83 | — | — | |
| Silicate SCHEMBL11490053 | 0.74 | GABRR1 (0.34) | GABRR1GABBR2GABBR1 | |
| SCHEMBL11322914 | 0.73 | — | — | |
| Butanol SCHEMBL27620184 | 0.72 | TSHR (0.67) | TDP1TSHR | |
| Propylamine SCHEMBL1685445 | 0.72 | TDP1 (0.53) | TDP1TSHR | |
| Ethylamine SCHEMBL612047 | 0.71 | TDP1 (0.61) | TDP1 | |
| SCHEMBL23017495 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120058057-A1 | Anti-dandruff Agents | MERCK PATENT GMBH (DE) | 2012-03-08 | — | — | US | claimed |
| US-20120058057-A1 | Anti-dandruff Agents | MERCK PATENT GMBH (DE) | 2012-03-08 | — | — | US | disclosed |
| WO-2010136105-A2 | AMMONIUMCARBOXYLATES | MERCK PATENT GMBH (DE) | 2010-12-02 | — | — | WO | disclosed |
| WO-2010136104-A2 | ANTI-DANDRUFF AGENTS | MERCK PATENT GMBH (DE) | 2010-12-02 | — | — | WO | disclosed |
| US-20100119461-A1 | ANTIMICROBIAL COMPOSITION | MERCK PATENT GMBH (DE) | 2010-05-13 | — | — | US | disclosed |
| EP-2112882-A2 | ANTIMICROBIAL COMPOSITION COMPRISING ZINC OXIDE, BARIUM SULPHATE AND SILVER IONS | Merck Patent GmbH (DE) | 2009-11-04 | — | — | EP | disclosed |
| WO-2008089822-A2 | ANTIMICROBIAL COMPOSITION COMPRISING ZINC OXIDE, BARIUM SULPHATE AND SILVER IONS | MERCK PATENT GMBH (DE) | 2008-07-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100119461-A1 | ANTIMICROBIAL COMPOSITION | ZFR, SOD1, NISCH | TDP1 3272/4885GABRR1 599/4885TSHR 1791/4885 |
| US-20120058057-A1 | Anti-dandruff Agents | POLR1C, ETF1, PIK3C3 | TDP1 968/4885GABRR1 346/4885TSHR 4265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.