Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | APAF1 | O14727 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | GALK1 | P51570 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14618928 | 1.00 | TDP2 (0.46) | TDP2MEN1NPC1MAPTKMT2A | |
| SCHEMBL14618912 | 0.91 | GSTP1 (0.42) | TDP2MEN1NPC1MAPTKMT2A | |
| SCHEMBL14618911 | 0.91 | GSTP1 (0.42) | TDP2MEN1NPC1MAPTKMT2A | |
| SCHEMBL14618909 | 0.91 | GSTP1 (0.42) | TDP2MEN1NPC1MAPTKMT2A | |
| SCHEMBL6253369 | 0.84 | HSD17B3 (0.51) | TDP2MEN1NPC1MAPTKMT2A | |
| Ammonia Solution, Strong SCHEMBL4888955 | 0.82 | HSD17B3 (0.50) | TDP2MEN1NPC1MAPTKMT2A | |
| SCHEMBL14586702 | 0.82 | GRM5 (0.51) | CYP1A2SRD5A1ESR1ESR2 | |
| SCHEMBL14586701 | 0.82 | GRM5 (0.51) | CYP1A2SRD5A1ESR1ESR2 | |
| SCHEMBL21028472 | 0.81 | HSD17B3 (0.49) | TDP2MEN1NPC1MAPTKMT2A | |
| SCHEMBL20160807 | 0.80 | LMNA (0.52) | MEN1NPC1MAPTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070037894-A1 | Multifunctional menomers and polyarylene compsotions therefrom | HAHNFELD JERRY L | 2007-02-15 | — | — | US | disclosed |