Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14619463 | 0.84 | ALDH1A1 (0.63) | KMT2AALDH1A1HTTMEN1POLB | |
| SCHEMBL14619461 | 0.83 | MEN1 (0.57) | KMT2AFFAR1ALDH1A1MAPTMAPK1 | |
| SCHEMBL15679198 | 0.80 | FFAR1 (0.60) | KMT2AFFAR1ALDH1A1MAPTMAPK1 | |
| SCHEMBL18475585 | 0.78 | APP (0.69) | FFAR1ALDH1A1MAPTMAPK1PARP10 | |
| SCHEMBL171857 | 0.78 | APP (0.69) | FFAR1ALDH1A1MAPTMAPK1PARP10 | |
| SCHEMBL5250063 | 0.77 | FFAR1 (1.00) | FFAR1POLBNPC1RAB9AF2RL1 | |
| SCHEMBL17054176 | 0.76 | ALDH1A1 (0.67) | KMT2AALDH1A1MAPTHTTMEN1 | |
| SCHEMBL14619239 | 0.76 | ALDH1A1 (0.54) | KMT2AFFAR1ALDH1A1MAPTMAPK1 | |
| SCHEMBL17054175 | 0.75 | KMT2A (0.54) | KMT2AFFAR1ALDH1A1MAPTGAA | |
| SCHEMBL13903016 | 0.73 | ALDH1A1 (0.67) | KMT2AALDH1A1MAPTHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946478-B1 | PROCESS FOR THE SOLID PHASE SYNTHESIS OF ALDEHYDES, KETONES AND HYDROXAMIC ACID COMPOUNDS | AVENTIS PHARMA INC (US) | 2007-02-14 | — | — | EP | disclosed |