Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.54 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 4/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3653038 | 0.84 | HDAC3 (0.62) | NPC1RAB9AMAPK1SMN1; SMN2 | |
| SCHEMBL14619087 | 0.83 | KMT2A (0.62) | MEN1KMT2AGAAFFAR1NPC1 | |
| SCHEMBL7042844 | 0.81 | HDAC2 (0.58) | FFAR1NPC1RAB9A | |
| SCHEMBL5794325 | 0.79 | HDAC3 (0.67) | NPC1RAB9AMAPT | |
| SCHEMBL19107583 | 0.79 | LTA4H (0.66) | FFAR1FFAR4LTA4HEPHX2LMNA | |
| SCHEMBL1860911 | 0.78 | FFAR1 (0.64) | FFAR1FFAR4LTA4HEPHX2NPC1 | |
| SCHEMBL7905578 | 0.78 | FFAR1 (0.82) | FFAR1FFAR4LTA4HEPHX2MAPK1 | |
| SCHEMBL9191952 | 0.77 | HDAC3 (0.71) | MEN1KMT2AGAALTA4HNPC1 | |
| SCHEMBL7046517 | 0.76 | ABCB1 (0.52) | FFAR1 | |
| SCHEMBL19825762 | 0.76 | FFAR1 (0.61) | FFAR1FFAR4LTA4HEPHX2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946478-B1 | PROCESS FOR THE SOLID PHASE SYNTHESIS OF ALDEHYDES, KETONES AND HYDROXAMIC ACID COMPOUNDS | AVENTIS PHARMA INC (US) | 2007-02-14 | — | — | EP | disclosed |