Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.53 |
| ▸ | RXRA | P19793 | 1/20 | 0.51 |
| ▸ | RXRB | P28702 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP14 | P50281 | 1/20 | 0.47 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12687835 | 0.82 | SMN1; SMN2 (0.63) | ALDH1A1MAPTMAPK1MAOBPARP10 | |
| SCHEMBL13929696 | 0.80 | APP (0.67) | ALDH1A1MAPTMAPK1MAOBPARP10 | |
| SCHEMBL14619244 | 0.80 | HDAC3 (0.55) | ALDH1A1MAPTMAPK1MAOBPARP10 | |
| SCHEMBL28563640 | 0.78 | MAOB (0.56) | ALDH1A1MAPTMAPK1MAOBPARP10 | |
| SCHEMBL14619087 | 0.76 | KMT2A (0.62) | ALDH1A1MAPTMAPK1MAOBMEN1 | |
| SCHEMBL9659998 | 0.74 | FFAR1 (0.71) | MAOBMEN1KMT2ARXRARXRB | |
| SCHEMBL14619461 | 0.74 | MEN1 (0.57) | ALDH1A1MAPTMAPK1MEN1KMT2A | |
| SCHEMBL14619462 | 0.73 | RAB9A (0.61) | ALDH1A1MAPTMAPK1MAOBPARP10 | |
| SCHEMBL14619088 | 0.72 | RAB9A (0.85) | ALDH1A1MAPTMAPK1MAOBPARP10 | |
| SCHEMBL8929713 | 0.72 | MAOB (0.69) | ALDH1A1MAPTMAPK1MAOBPARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946478-B1 | PROCESS FOR THE SOLID PHASE SYNTHESIS OF ALDEHYDES, KETONES AND HYDROXAMIC ACID COMPOUNDS | AVENTIS PHARMA INC (US) | 2007-02-14 | — | — | EP | disclosed |