Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.55 |
| ▸ | MEN1 | O00255 | 8/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | APP | P05067 | 6/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | S100A4 | P26447 | 1/20 | 0.52 |
| ▸ | INSR | P06213 | 1/20 | 0.52 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | HBB | P68871 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10371974 | 0.89 | RELA (0.63) | MAPTMEN1KMT2ARAB9AMAPK1 | |
| SCHEMBL10435447 | 0.89 | RELA (0.63) | MAPTMEN1KMT2ARAB9AMAPK1 | |
| SCHEMBL14027211 | 0.82 | NPC1 (0.50) | MAPTMEN1KMT2ARAB9AMAPK1 | |
| SCHEMBL10435351 | 0.80 | APP (0.61) | MAPTMEN1KMT2ARAB9AMAPK1 | |
| SCHEMBL15958645 | 0.79 | MAPT (0.52) | MAPTMEN1KMT2ARAB9AMAPK1 | |
| SCHEMBL30464972 | 0.78 | MAPT (0.61) | MAPTMEN1KMT2ARAB9AMAPK1 | |
| SCHEMBL12669913 | 0.76 | MAPT (0.49) | MAPTMEN1KMT2ARAB9AMAPK1 | |
| SCHEMBL5613592 | 0.76 | RELA (0.51) | MAPTMEN1KMT2ARAB9AMAPK1 | |
| SCHEMBL12676802 | 0.76 | S100A4 (0.50) | MAPTMEN1KMT2ARAB9AMAPK1 | |
| SCHEMBL9000562 | 0.76 | MAPT (0.64) | MAPTMEN1KMT2ARAB9AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7176208-B2 | Prevent reproduction of hepatitis virus | ENANTA PHARMACEUTICALS, INC. (US) | 2007-02-13 | — | — | US | disclosed |