Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 2/20 | 0.34 |
| ▸ | FNTB | P49356 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14619570 | 0.84 | MAPT (0.36) | ALDH1A1CYP2D6CYP2C19TSHRHPGD | |
| SCHEMBL14619567 | 0.84 | FAAH (0.36) | ALDH1A1CYP2D6CYP2C19TSHRPOLB | |
| SCHEMBL16897675 | 0.82 | ALOX15 (0.51) | ALOX15ALDH1A1CYP2D6CYP2C19TSHR | |
| SCHEMBL14606153 | 0.76 | ALOX15 (0.58) | ALOX15ALDH1A1CYP2D6CYP2C19TSHR | |
| SCHEMBL14619568 | 0.73 | CYP3A4 (0.33) | CYP2C19 | |
| SCHEMBL16599025 | 0.73 | ALDH1A1 (0.42) | ALOX15ALDH1A1CYP2D6CYP2C19TSHR | |
| SCHEMBL20773608 | 0.72 | ALOX15 (0.36) | ALOX15ALDH1A1CYP2D6CYP2C19TSHR | |
| SCHEMBL10837285 | 0.71 | ALDH1A1 (0.41) | ALOX15ALDH1A1CYP2D6CYP2C19HPGD | |
| SCHEMBL20778827 | 0.71 | FNTA (0.45) | ALOX15ALDH1A1TSHRFNTAFNTB | |
| SCHEMBL9577318 | 0.71 | ALOX15 (0.39) | ALOX15ALDH1A1TSHRFNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7176208-B2 | Prevent reproduction of hepatitis virus | ENANTA PHARMACEUTICALS, INC. (US) | 2007-02-13 | — | — | US | disclosed |