Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13455246 | 0.87 | LMNA (0.39) | LMNAPOLBRIPK1L3MBTL1NPC1 | |
| SCHEMBL12976000 | 0.82 | LMNA (0.35) | LMNAPOLBRIPK1L3MBTL1NPC1 | |
| SCHEMBL16316421 | 0.77 | ADORA1 (0.56) | LMNAPOLBL3MBTL1NPC1RAB9A | |
| SCHEMBL1948564 | 0.74 | CNR2 (0.50) | LMNAPOLBRIPK1L3MBTL1CNR2 | |
| SCHEMBL12226380 | 0.74 | L3MBTL1 (0.61) | LMNAPOLBRIPK1L3MBTL1CNR2 | |
| SCHEMBL14108279 | 0.73 | MEN1 (0.41) | LMNAPOLBL3MBTL1MEN1KMT2A | |
| SCHEMBL14612453 | 0.72 | MEN1 (0.46) | CNR2MEN1KMT2AADORA1CNR1 | |
| SCHEMBL17829466 | 0.72 | BRD4 (0.39) | LMNAPOLBRIPK1L3MBTL1NPC1 | |
| SCHEMBL13134415 | 0.71 | MDM2 (0.52) | LMNAPOLBL3MBTL1RAB9AMEN1 | |
| SCHEMBL14649768 | 0.71 | GAA (0.43) | LMNAPOLBRIPK1L3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7179872-B2 | Chain transfer agents for RAFT polymerization in aqueous media | UNIVERSITY OF SOUTHERN MISSISSIPPI (US) | 2007-02-20 | — | — | US | disclosed |