Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 4/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10175725 | 0.82 | MAPT (0.46) | L3MBTL1NPC1RAB9ALMNAPOLB | |
| SCHEMBL13446577 | 0.78 | KMT2A (0.37) | L3MBTL1NPC1RAB9ALMNAPOLB | |
| SCHEMBL2294837 | 0.76 | — | — | |
| SCHEMBL10225946 | 0.75 | LMNA (0.43) | L3MBTL1NPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL3645380 | 0.75 | CA2 (0.38) | L3MBTL1NPC1RAB9AALDH1A1HTT | |
| SCHEMBL9129001 | 0.72 | CYP2C19 (0.46) | MAPTSMN1; SMN2HSD17B10 | |
| SCHEMBL13446579 | 0.72 | ABL1 (0.40) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL14619635 | 0.72 | LMNA (0.44) | BRD4L3MBTL1NPC1RAB9ALMNA | |
| SCHEMBL12057465 | 0.72 | MDM2 (0.33) | — | |
| SCHEMBL9128672 | 0.71 | CYP2C19 (0.45) | MAPTSMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160168302-A1 | SEPARATING AGENT | NATIONAL UNIVERSITY CORPORATION KYOTO INSTITUTE OF TECHNOLOGY (JP) | 2016-06-16 | — | — | US | disclosed |